User profiles for Veronique Gigoux
 | Veronique Gigouxinserm Verified email at inserm.fr Cited by 1621 |
[HTML][HTML] Magneto-mechanical destruction of cancer-associated fibroblasts using ultra-small iron oxide nanoparticles and low frequency rotating magnetic fields
The destruction of cells using the mechanical activation of magnetic nanoparticles with low-frequency
magnetic fields constitutes a recent and interesting approach in cancer therapy. …
magnetic fields constitutes a recent and interesting approach in cancer therapy. …
Targeting a G-protein-coupled receptor overexpressed in endocrine tumors by magnetic nanoparticles to induce cell death
Nanotherapy using targeted magnetic nanoparticles grafted with peptidic ligands of receptors
overexpressed in cancers is a promising therapeutic strategy. However, nanoconjugation …
overexpressed in cancers is a promising therapeutic strategy. However, nanoconjugation …
Targeted Magnetic Intra-Lysosomal Hyperthermia produces lysosomal reactive oxygen species and causes Caspase-1 dependent cell death
Therapeutic strategies using drugs which cause Lysosomal Cell Death have been proposed
for eradication of resistant cancer cells. In this context, nanotherapy based on Magnetic Intra…
for eradication of resistant cancer cells. In this context, nanotherapy based on Magnetic Intra…
Real‐time analysis of magnetic hyperthermia experiments on living cells under a confocal microscope
…, P Clerc, N Hallali, D El Hajj Diab, D Fourmy, V Gigoux… - Small, 2015 - Wiley Online Library
Combining high‐frequency alternating magnetic fields (AMF) and magnetic nanoparticles (MNPs)
is an efficient way to induce biological responses through several approaches: …
is an efficient way to induce biological responses through several approaches: …
SH2 and SH3 domains as targets for anti-proliferative agents
M Vidal, V Gigoux, C Garbay - Critical reviews in oncology/hematology, 2001 - Elsevier
The Src homology domains SH2 and SH3 are small modular protein motifs about 100 and
60 amino acids long, respectively. SH2 domains interact with phosphotyrosine residues, …
60 amino acids long, respectively. SH2 domains interact with phosphotyrosine residues, …
[HTML][HTML] Pharmacologic normalization of pancreatic cancer-associated fibroblast secretome impairs prometastatic cross-talk with macrophages
Background & Aims Cancer-associated fibroblasts (CAFs) from pancreatic adenocarcinoma
(PDA) present high protein synthesis rates. CAFs express the G-protein–coupled …
(PDA) present high protein synthesis rates. CAFs express the G-protein–coupled …
Internalized receptor for glucose-dependent insulinotropic peptide stimulates adenylyl cyclase on early endosomes
…, MJ Gherardi, A Froese, M Zanoun, V Gigoux… - Biochemical …, 2016 - Elsevier
Until very recently, G-protein dependent signal of GPCRs was thought to originate exclusively
from the plasma membrane and internalized GPCRs were considered silent. Here, we …
from the plasma membrane and internalized GPCRs were considered silent. Here, we …
Real-time observation and analysis of magnetomechanical actuation of magnetic nanoparticles in cells
The origin of cell death in the magnetomechanical actuation of cells induced by magnetic
nanoparticle motion under low-frequency magnetic fields is still elusive. Here, a miniaturized …
nanoparticle motion under low-frequency magnetic fields is still elusive. Here, a miniaturized …
[HTML][HTML] Oxidative stress induced by inactivation of TP53INP1 cooperates with KrasG12D to initiate and promote pancreatic carcinogenesis in the murine pancreas
…, N Hanoun, S Peuget, H Lulka, V Gigoux… - The American journal of …, 2013 - Elsevier
Tumor protein p53-induced nuclear protein 1 (TP53INP1) is involved in cell stress response.
Its expression is lost at the pancreatic intraepithelial neoplasia 1b (PanIN1b)/PanIN2 stage …
Its expression is lost at the pancreatic intraepithelial neoplasia 1b (PanIN1b)/PanIN2 stage …
[HTML][HTML] The biologically crucial C terminus of cholecystokinin and the non-peptide agonist SR-146,131 share a common binding site in the human CCK1 receptor …
C Escrieut, V Gigoux, E Archer, S Verrier… - Journal of Biological …, 2002 - ASBMB
The cholecystokinin (CCK) receptor-1 (CCK1R) is a G protein-coupled receptor, which
mediates important central and peripheral cholecystokinin actions. Our aim was to progress in …
mediates important central and peripheral cholecystokinin actions. Our aim was to progress in …