Fractalkine modulates TNF‐α secretion and neurotoxicity induced by microglial activation
V Zujovic, J Benavides, X Vigé, C Carter, V Taupin - Glia, 2000 - Wiley Online Library
Among the chemokine family, fractalkine shows unusual properties: it exists as a membrane‐bound
and soluble protein, and both fractalkine and its receptor CX 3 CR1 are expressed …
and soluble protein, and both fractalkine and its receptor CX 3 CR1 are expressed …
Adaptive human immunity drives remyelination in a mouse model of demyelination
…, H Abdi, I Cournu-Rebeix, B Fontaine, V Zujovic - Brain, 2017 - academic.oup.com
One major challenge in multiple sclerosis is to understand the cellular and molecular
mechanisms leading to disease severity progression. The recently demonstrated correlation …
mechanisms leading to disease severity progression. The recently demonstrated correlation …
In vivo neutralization of endogenous brain fractalkine increases hippocampal TNFα and 8-isoprostane production induced by intracerebroventricular injection of LPS
V Zujovic, N Schussler, D Jourdain, D Duverger… - Journal of …, 2001 - Elsevier
Fractalkine is a chemokine widely and constitutively expressed in the brain and, as suggested
by in vitro studies, it is involved in brain inflammatory responses. In this study, we have …
by in vitro studies, it is involved in brain inflammatory responses. In this study, we have …
Modulation of the innate immune response by human neural precursors prevails over oligodendrocyte progenitor remyelination to rescue a severe model of Pelizaeus …
…, C Deboux, MD Santin, P Gressens, V Zujovic… - Stem Cells, 2016 - academic.oup.com
Pelizaeus-Merzbacher disease (PMD) results from an X-linked misexpression of proteolipid
protein 1 (PLP1). This leukodystrophy causes severe hypomyelination with progressive …
protein 1 (PLP1). This leukodystrophy causes severe hypomyelination with progressive …
Use of cocultured cell systems to elucidate chemokine-dependent neuronal/microglial interactions: control of microglial activation
V Zujovic, V Taupin - Methods, 2003 - Elsevier
In order to understand processes involved in central nervous system inflammatory diseases,
a critical appreciation of mechanisms involved in the control of immune function in the brain …
a critical appreciation of mechanisms involved in the control of immune function in the brain …
Boundary cap cells are peripheral nervous system stem cells that can be redirected into central nervous system lineages
V Zujovic, J Thibaud, C Bachelin… - Proceedings of the …, 2011 - National Acad Sciences
Boundary cap cells (BC), which express the transcription factor Krox20, participate in the
formation of the boundary between the central nervous system and the peripheral nervous …
formation of the boundary between the central nervous system and the peripheral nervous …
Activation of macrophages by lysophosphatidic acid through the lysophosphatidic acid receptor 1 as a novel mechanism in multiple sclerosis pathogenesis
…, C Louapre, AB Van-Evercooren, V Zujovic… - Molecular …, 2021 - Springer
Multiple sclerosis (MS) is a neuroinflammatory disease whose pathogenesis remains unclear.
Lysophosphatidic acid (LPA) is an endogenous phospholipid involved in multiple immune …
Lysophosphatidic acid (LPA) is an endogenous phospholipid involved in multiple immune …
Resistance to induced apoptosis in the human neuroblastoma cell line SK‐N‐SH in relation to neuronal differentiation: Role of Bcl‐2 protein family
A Lombet, V Zujovic, M Kandouz… - European journal of …, 2001 - Wiley Online Library
Much evidence suggests that apoptosis plays a crucial role in cell population homeostasis
that depends on the expression of various genes implicated in the control of cell life and death…
that depends on the expression of various genes implicated in the control of cell life and death…
[HTML][HTML] Efficacy of HDAC Inhibitors in Driving Peroxisomal β-Oxidation and Immune Responses in Human Macrophages: Implications for Neuroinflammatory …
…, B Zierfuss, P Parzer, E Heuböck, V Zujovic… - Biomolecules, 2023 - mdpi.com
Elevated levels of saturated very long-chain fatty acids (VLCFAs) in cell membranes and
secreted lipoparticles have been associated with neurotoxicity and, therefore, require tight …
secreted lipoparticles have been associated with neurotoxicity and, therefore, require tight …
Myelin-associated glycoprotein inhibits schwann cell migration and induces their death
N Chaudhry, C Bachelin, V Zujovic… - Journal of …, 2017 - Soc Neuroscience
Remyelination of CNS axons by Schwann cells (SCs) is not efficient, in part due to the poor
migration of SCs into the adult CNS. Although it is known that migrating SCs avoid white …
migration of SCs into the adult CNS. Although it is known that migrating SCs avoid white …