RETRACTED: Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability …

…, HB Nair, B Sung, AB Kunnumakkara, VR Yadav… - 2010 - Elsevier
Curcumin, a yellow pigment present in the spice turmeric (Curcuma longa), has been linked
with antioxidant, anti-inflammatory, antiproliferative, anticancer, antidiabetic, antirheumatic, …

The role of chalcones in suppression of NF-κB-mediated inflammation and cancer

VR Yadav, S Prasad, B Sung, BB Aggarwal - International …, 2011 - Elsevier
Although consumption of fruits, vegetables, spices, cereals and pulses has been associated
with lower incidence of cancer and other chronic diseases, how these dietary agents and …

[HTML][HTML] Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer

VR Yadav, S Prasad, B Sung, R Kannappan… - Toxins, 2010 - mdpi.com
Traditional medicine and diet has served mankind through the ages for prevention and
treatment of most chronic diseases. Mounting evidence suggests that chronic inflammation …

Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases:“reverse pharmacology” and “bedside to bench” approach

…, S Reuter, R Kannappan, VR Yadav… - Current drug …, 2011 - ingentaconnect.com
Inflammation, although first characterized by Cornelius Celsus, a physician in first Century
Rome, it was Rudolf Virchow, a German physician in nineteenth century who suggested a link …

Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer

HB Nair, B Sung, VR Yadav, R Kannappan… - Biochemical …, 2010 - Elsevier
Extensive research within the last two decades has revealed that most chronic illnesses,
including cancer, diabetes, and cardiovascular and pulmonary diseases, are mediated through …

Effect of cyclodextrin complexation of curcumin on its solubility and antiangiogenic and anti-inflammatory activity in rat colitis model

VR Yadav, S Suresh, K Devi, S Yadav - Aaps Pharmscitech, 2009 - Springer
The purpose of the study was to prepare and evaluate the anti-inflammatory activity of
cyclodextrin (CD) complex of curcumin for the treatment of inflammatory bowel disease (IBD) in …

[HTML][HTML] Targeting inflammatory pathways by flavonoids for prevention and treatment of cancer

S Prasad, K Phromnoi, VR Yadav… - Planta …, 2010 - thieme-connect.com
Observational studies have suggested that lifestyle risk factors such as tobacco, alcohol,
high-fat diet, radiation, and infections can cause cancer and that a diet consisting of fruits and …

Cancer cell signaling pathways targeted by spice-derived nutraceuticals

B Sung, S Prasad, VR Yadav, BB Aggarwal - Nutrition and cancer, 2012 - Taylor & Francis
Extensive research within the last half a century has revealed that cancer is caused by
dysregulation of as many as 500 different gene products. Most natural products target multiple …

Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways …

…, VR Yadav, B Sung, S Reuter, R Kannappan… - Clinical cancer …, 2012 - AACR
Purpose: Development of chemoresistance, poor prognosis, and metastasis often renders
the current treatments for colorectal cancer (CRC) ineffective. Whether ursolic acid, a …

Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)‐κB and NF‐κB‐regulated gene products and induces death receptors leading to suppressed …

JH Kim, SC Gupta, B Park, VR Yadav… - Molecular nutrition & …, 2012 - Wiley Online Library
Scope The incidence of cancer is significantly lower in regions where turmeric is heavily
consumed. Whether lower cancer incidence is due to turmeric was investigated by examining its …