Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy

…, HH Tseng, CW Peng, WS Chen… - … journal of oncology, 2012 - spandidos-publications.com
The outcome of producing apoptotic defects in cancer cells is the primary obstacle that limits
the therapeutic efficacy of anticancer agents, and hence the development of novel agents …

[HTML][HTML] Lapatinib–induced NF-kappaB activation sensitizes triple-negative breast cancer cells to proteasome inhibitors

…, WS Chen, JY Chen, CY Shih, CY Tu, CH Chen… - Breast cancer …, 2013 - Springer
Introduction Triple-negative breast cancer (TNBC), a subtype of breast cancer with negative
expressions of estrogen receptor, progesterone receptor, and human epidermal growth …

[HTML][HTML] Factors associated with peripheral blood stem cell yield in volunteer donors mobilized with granulocyte colony-stimulating factors: the impact of donor …

TF Wang, SH Wen, RL Chen, CJ Lu, YJ Zheng… - Biology of Blood and …, 2008 - Elsevier
Peripheral blood stem cells (PBSCs) are increasingly used as the source of hematopoietic
stem cells, but there are large variations in harvest outcome between individuals mobilized by …

Regulation on copper-tolerance in Citrus sinensis seedlings by boron addition: Insights from root exudates, related metabolism, and gene expression

HH Chen, ZC Zheng, WS Chen, RY Rao… - Journal of Hazardous …, 2023 - Elsevier
Boron (B) can alleviate Citrus copper (Cu)-toxicity. However, the underlying mechanism by
which B mitigates Cu-toxicity is unclear. ‘Xuegan’ (Citrus sinensis) seedlings were exposed …

Novel diagnosis and treatment of esophageal granular cell tumor: report of 14 cases and review of the literature

W Chen, X Zheng, L Jin, X Pan, M Ye - The Annals of thoracic surgery, 2014 - Elsevier
Background Granular cell tumors (GCT), especially in the esophagus, are rare neoplasms
originating from the nervous system. There is still some controversy regarding the diagnosis …

[HTML][HTML] Next-generation sequencing-based quantitative detection of hepatitis B virus pre-S mutants in plasma predicts hepatocellular carcinoma recurrence

CF Teng, TC Li, HY Huang, JH Lin, WS Chen… - Viruses, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is among the most common and lethal human cancers
worldwide. Despite curative resection, high recurrence of HCC remains a big threat, leading to …

Circular RNA WHSC1 exerts oncogenic properties by regulating miR‐7/TAB2 in lung cancer

…, J Wang, Q Gui, CC Xu, Y Cheng… - Journal of cellular …, 2021 - Wiley Online Library
Circular RNA is a newly discovered member of non‐coding RNA (ncRNA) and regulates the
target gene by acting as a micro‐RNA sponge. It plays vital roles in various diseases. …

[HTML][HTML] Circ_0044516 regulates miR-136/MAT2A pathway to facilitate lung cancer development

YW Chen, QR Du, YJ He, WS Chen… - Journal of immunology …, 2021 - hindawi.com
Circular RNA (circRNA) is a type of noncoding RNA that can interact with miRNAs to regulate
gene expression. However, little is known concerning circRNA, which is crucial in the …

[HTML][HTML] miRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin

WS Chen, CJ Yen, YJ Chen, JY Chen, LY Wang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Maspin suppresses tumor progression by promoting cell adhesion and apoptosis and by
inhibiting cell motility. However, its role in tumorigenesis of hepatocellular carcinoma (HCC) …

[HTML][HTML] Hepatitis B virus-encoded X protein downregulates EGFR expression via inducing microRNA-7 in hepatocellular carcinoma cells

YJ Chen, PH Chien, WS Chen, YF Chien… - Evidence-based …, 2013 - hindawi.com
Hepatitis B virus (HBV) infection accounts for over a half of cases of hepatocellular carcinoma
(HCC), the most frequent malignant tumor of the liver. HBV-encoded X (HBx) plays critical …