User profiles for Xu Shen

Shen Xu

City University of Hong Kong
Verified email at cityu.edu.hk
Cited by 1361

Virtual screening on natural products for discovering active compounds and target information

…, J Shen, K Chen, W Zhao, X Shen… - Current medicinal …, 2003 - ingentaconnect.com
Natural products, containing inherently large-scale structural diversity than synthetic
compounds, have been the major resources of bioactive agents and will continually play as …

Microplastics in aquatic environments: occurrence, accumulation, and biological effects

S Xu, J Ma, R Ji, K Pan, AJ Miao - Science of the Total Environment, 2020 - Elsevier
Microplastics, whether originating directly from industrial and household products or from the
degradation of larger plastics, are currently of intense global concern. These particles are …

Excited state modulation for organic afterglow: materials and applications

S Xu, R Chen, C Zheng, W Huang - Advanced Materials, 2016 - Wiley Online Library
Organic afterglow materials, developed recently by breaking through the difficulties in
modulating ultrafast‐decayed excited states, exhibit ultralong‐lived emission for persistent …

Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin

…, Y Luo, H Guo, RD Jiang, MQ Liu, Y Chen, XR Shen… - BioRxiv, 2020 - biorxiv.org
Since the SARS outbreak 18 years ago, a large number of severe acute respiratory syndrome
related coronaviruses (SARSr-CoV) have been discovered in their natural reservoir host, …

Fast and highly efficient tetracyclines removal from environmental waters by graphene oxide functionalized magnetic particles

Y Lin, S Xu, J Li - Chemical Engineering Journal, 2013 - Elsevier
The extensive use of tetracycline antibiotics (TCs) has caused a lot of environmental pollution.
In our study, graphene oxide functionalized magnetic particles (GO-MPs) were prepared …

[HTML][HTML] A pneumonia outbreak associated with a new coronavirus of probable bat origin

…, Y Luo, H Guo, RD Jiang, MQ Liu, Y Chen, XR Shen… - nature, 2020 - nature.com
Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large
number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural …

Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance

…, L Chen, C Li, L Hu, H Jiang, X Shen - Journal of …, 2013 - Soc Neuroscience
Alzheimer's disease (AD) chiefly characterizes a progressively neurodegenerative disorder
of the brain, and eventually leads to irreversible loss of intellectual abilities. The β-amyloid (…

[HTML][HTML] Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus

…, XY Ge, W Zhang, B Li, JZ Xie, XR Shen… - PLoS …, 2017 - journals.plos.org
A large number of SARS-related coronaviruses (SARSr-CoV) have been detected in
horseshoe bats since 2005 in different areas of China. However, these bat SARSr-CoVs show …

[HTML][HTML] G protein-coupled estrogen receptor: a potential therapeutic target in cancer

S Xu, S Yu, D Dong, LTO Lee - Frontiers in endocrinology, 2019 - frontiersin.org
The G protein-coupled estrogen receptor (GPER) is a seven-transmembrane-domain
receptor that mediates non-genomic estrogen related signaling. After ligand activation, GPER …

[PDF][PDF] Pathogenesis of SARS-CoV-2 in transgenic mice expressing human angiotensin-converting enzyme 2

…, MQ Liu, Y Chen, C Shan, YW Zhou, XR Shen… - Cell, 2020 - cell.com
COVID-19 has spread worldwide since 2019 and is now a severe threat to public health.
We previously identified the causative agent as a novel SARS-related coronavirus (SARS-CoV-…