User profiles for Yoo-Hun Suh
Yoo-Hun SuhDept. Pharmacology,College of Medicine,Seoul National University.Neuroscience Research … Verified email at snu.ac.kr Cited by 11231 |
Nanotechnology, nanotoxicology, and neuroscience
Nanotechnology, which deals with features as small as a 1 billionth of a meter, began to
enter into mainstream physical sciences and engineering some 20 years ago. Recent …
enter into mainstream physical sciences and engineering some 20 years ago. Recent …
Amyloid precursor protein, presenilins, and α-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease
Alzheimer's disease (AD) is the most common cause of dementia that arises on a
neuropathological background of amyloid plaques containing β-amyloid (Aβ) derived from amyloid …
neuropathological background of amyloid plaques containing β-amyloid (Aβ) derived from amyloid …
Minocycline and neurodegenerative diseases
HS Kim, YH Suh - Behavioural brain research, 2009 - Elsevier
Minocycline is a semi-synthetic, second-generation tetracycline analog which is effectively
crossing the blood–brain barrier, effective against gram-positive and -negative infections. In …
crossing the blood–brain barrier, effective against gram-positive and -negative infections. In …
[HTML][HTML] Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models
Minocycline is a semi-synthetic tetracycline antibiotic that effectively crosses the blood–brain
barrier. Minocycline has been reported to have significant neuroprotective effects in models …
barrier. Minocycline has been reported to have significant neuroprotective effects in models …
C‐terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase‐3β expression
The AICD (amyloid precursor protein [APP] intracellular domain) and C31, the caspase‐cleaved
C‐terminal fragment of APP, have been found in the brains of patients with Alzheimer's …
C‐terminal fragment of APP, have been found in the brains of patients with Alzheimer's …
Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model
…, SM Ahn, HS Kim, SH Lee, PC Emson, YH Suh - 2006 - s-space.snu.ac.kr
Although chronic stress is known to be linked with memory and other neurological disorders,
little is known about the relationship between chronic stress and the onset or development …
little is known about the relationship between chronic stress and the onset or development …
Block of LTP in rat hippocampus in vivo by β-amyloid precursor protein fragments
WK Cullen, YH Suh, R Anwyl, MJ Rowan - Neuroreport, 1997 - journals.lww.com
THE effects of β-amyloid precursor protein (β-APP) fragments on plasticity of glutamtatergic
synaptic transmission were examined in the hippocampus of urethane anaesthetized rats. Icv …
synaptic transmission were examined in the hippocampus of urethane anaesthetized rats. Icv …
α‐Synuclein regulates neuronal survival via Bcl‐2 family expression and PI3/Akt kinase pathway
α‐Synuclein (α‐SN) is a ubiquitous protein that is especially abundant in the brain and has
been postulated to play a central role in the pathogenesis of Parkinson's disease, …
been postulated to play a central role in the pathogenesis of Parkinson's disease, …
Use-dependent effects of amyloidogenic fragments of β-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo
The Alzheimer's disease-related β-amyloid precursor protein (β-APP) is metabolized to a
number of potentially amyloidogenic peptides that are believed to be pathogenic. Application of …
number of potentially amyloidogenic peptides that are believed to be pathogenic. Application of …
[HTML][HTML] The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer's disease mice
…, KA Chang, JA Kim, HG Park, JC Ra, HS Kim, YH Suh - 2012 - journals.plos.org
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid plaques and
neurofibrillary tangles accompanied by cognitive dysfunction. The aim of the present study was to …
neurofibrillary tangles accompanied by cognitive dysfunction. The aim of the present study was to …