User profiles for Yoo-Hun Suh

Yoo-Hun Suh

Dept. Pharmacology,College of Medicine,Seoul National University.Neuroscience Research …
Verified email at snu.ac.kr
Cited by 11231

Nanotechnology, nanotoxicology, and neuroscience

WH Suh, KS Suslick, GD Stucky, YH Suh - Progress in neurobiology, 2009 - Elsevier
Nanotechnology, which deals with features as small as a 1 billionth of a meter, began to
enter into mainstream physical sciences and engineering some 20 years ago. Recent …

Amyloid precursor protein, presenilins, and α-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease

YH Suh, F Checler - Pharmacological reviews, 2002 - ASPET
Alzheimer's disease (AD) is the most common cause of dementia that arises on a
neuropathological background of amyloid plaques containing β-amyloid (Aβ) derived from amyloid …

Minocycline and neurodegenerative diseases

HS Kim, YH Suh - Behavioural brain research, 2009 - Elsevier
Minocycline is a semi-synthetic, second-generation tetracycline analog which is effectively
crossing the blood–brain barrier, effective against gram-positive and -negative infections. In …

[HTML][HTML] Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models

…, J Yoo, JP Lee, KA Chang, S Kim, YH Suh - …, 2007 - nature.com
Minocycline is a semi-synthetic tetracycline antibiotic that effectively crosses the blood–brain
barrier. Minocycline has been reported to have significant neuroprotective effects in models …

C‐terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase‐3β expression

…, E Yu, SJ Jeong, YH Chong, YH Suh - The FASEB …, 2003 - Wiley Online Library
The AICD (amyloid precursor protein [APP] intracellular domain) and C31, the caspase‐cleaved
C‐terminal fragment of APP, have been found in the brains of patients with Alzheimer's …

Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model

…, SM Ahn, HS Kim, SH Lee, PC Emson, YH Suh - 2006 - s-space.snu.ac.kr
Although chronic stress is known to be linked with memory and other neurological disorders,
little is known about the relationship between chronic stress and the onset or development …

Block of LTP in rat hippocampus in vivo by β-amyloid precursor protein fragments

WK Cullen, YH Suh, R Anwyl, MJ Rowan - Neuroreport, 1997 - journals.lww.com
THE effects of β-amyloid precursor protein (β-APP) fragments on plasticity of glutamtatergic
synaptic transmission were examined in the hippocampus of urethane anaesthetized rats. Icv …

α‐Synuclein regulates neuronal survival via Bcl‐2 family expression and PI3/Akt kinase pathway

…, SH Lee, S Lee, S Won Suh, YH Suh - The FASEB …, 2002 - Wiley Online Library
α‐Synuclein (α‐SN) is a ubiquitous protein that is especially abundant in the brain and has
been postulated to play a central role in the pathogenesis of Parkinson's disease, …

Use-dependent effects of amyloidogenic fragments of β-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo

JH Kim, R Anwyl, YH Suh, MBA Djamgoz… - Journal of …, 2001 - Soc Neuroscience
The Alzheimer's disease-related β-amyloid precursor protein (β-APP) is metabolized to a
number of potentially amyloidogenic peptides that are believed to be pathogenic. Application of …

[HTML][HTML] The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer's disease mice

…, KA Chang, JA Kim, HG Park, JC Ra, HS Kim, YH Suh - 2012 - journals.plos.org
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid plaques and
neurofibrillary tangles accompanied by cognitive dysfunction. The aim of the present study was to …