[PDF][PDF] Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease
B Meresse, Z Chen, C Ciszewski, M Tretiakova… - Immunity, 2004 - cell.com
A major function of NKG2D linking innate and adaptive immunity is to upregulate antigen-specific
CTL-mediated cytotoxicity in tissues expressing stress-induced NKG2D ligands, such …
CTL-mediated cytotoxicity in tissues expressing stress-induced NKG2D ligands, such …
Modulation of Ca2+ entry by polypeptides of the inositol 1,4,5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in …
Homologues of Drosophilia transient receptor potential (TRP) have been proposed to be
unitary subunits of plasma membrane ion channels that are activated as a consequence of …
unitary subunits of plasma membrane ion channels that are activated as a consequence of …
Activation of Trp3 by inositol 1, 4, 5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain
…, S Tikunova, JD Johnson, Z Chen… - Proceedings of the …, 2001 - National Acad Sciences
Mammalian homologues of Drosophila Trp form plasma membrane channels that mediate
Ca 2+ influx in response to activation of phospholipase C and internal Ca 2+ store depletion. …
Ca 2+ influx in response to activation of phospholipase C and internal Ca 2+ store depletion. …
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8−CD11b+ dendritic cells
…, JT Andersen, I Sandlie, Z Chen… - Proceedings of the …, 2011 - National Acad Sciences
Cross-presentation of IgG-containing immune complexes (ICs) is an important means by
which dendritic cells (DCs) activate CD8 + T cells, yet it proceeds by an incompletely …
which dendritic cells (DCs) activate CD8 + T cells, yet it proceeds by an incompletely …
[HTML][HTML] Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF
Y Tang, J Tang, Z Chen, C Trost, V Flockerzi… - Journal of Biological …, 2000 - ASBMB
Mammalian homologues of DrosophilaTrp have been implicated to form channels that are
activated following the depletion of Ca 2+ from internal stores. Recent studies indicate that …
activated following the depletion of Ca 2+ from internal stores. Recent studies indicate that …
[PDF][PDF] SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms
T cell activation through the T cell receptor (TCR) is subsequently modified by secondary
signals that are either stimulatory or inhibitory. We show that CEACAM1 adhesion molecule …
signals that are either stimulatory or inhibitory. We show that CEACAM1 adhesion molecule …
Tumor immune microenvironment in head and neck cancers
SMY Chen, AL Krinsky, RA Woolaver… - Molecular …, 2020 - Wiley Online Library
Head and neck cancers are a heterogeneous group of tumors that are highly aggressive
and collectively represent the sixth most common cancer worldwide. Ninety percent of head …
and collectively represent the sixth most common cancer worldwide. Ninety percent of head …
[PDF][PDF] Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer
Cancers arising in mucosal tissues account for a disproportionately large fraction of
malignancies. Immunoglobulin G (IgG) and the neonatal Fc receptor for IgG (FcRn) have an …
malignancies. Immunoglobulin G (IgG) and the neonatal Fc receptor for IgG (FcRn) have an …
Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15
F Tang, Z Chen, C Ciszewski, M Setty, J Solus… - Journal of Experimental …, 2009 - rupress.org
IL-15 and NKG2D promote autoimmunity and celiac disease by arming cytotoxic T
lymphocytes (CTLs) to cause tissue destruction. However, the downstream signaling events …
lymphocytes (CTLs) to cause tissue destruction. However, the downstream signaling events …
[HTML][HTML] Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function
…, DC Barral, Y Junker, Z Chen… - The Journal of …, 2010 - Am Soc Clin Investig
Abetalipoproteinemia (ABL) is a rare Mendelian disorder of lipid metabolism due to genetic
deficiency in microsomal triglyceride transfer protein (MTP). It is associated with defects in …
deficiency in microsomal triglyceride transfer protein (MTP). It is associated with defects in …