A complex of calf-thymus DNA with berberine sediments in the analytical ultracentrifuge. The
DNA produced systematic changes in the absorption spectrum of berberine which suggest …

… We reported (Krey and Hahn, 1974) that the concentrations of quinacrine (Qua) addedto the
MG-DNA solution (1.88 X 10-5 M MG) determined whether the displacement reaction was of …

Double-helical calf thymus DNA and poly dG:dC produced marked changes in the absorption
spectrum of quinine. Single-stranded DNA, poly dA:dT, and poly dI:dC were without effect. …

The antibiotic, distamycin A (DMC, fig. l), has the unique property of inhibiting induced enzyme
synthesis in bacteria [l]. This provides a potential tool in the study of regulatory processes …

The complex of distamycin A (DMC) with DNA is very stable: neither dialysis against 1%
sodium lauryl sulfate [l] nor treatment with 6 M urea or with physiological concentrations of …

Many biologically active substances produce their genetic, biochemical, pharmacological,
and tinctorial effects as consequences of their interactions with DNA. Binding to the nucleic …

The binding of the drug quinacrine to its bioreceptor, DNA, was studied by optical methods.
Binding of quinacrine to duplex calf thymus DNA produced bathochromic shifts in the …

Developmentally caused skin malformations constitute a spectrum of birth defects, some of
which can be recognized prenatally by morphologic or biochemical means. The number of …

… Mter it was found (HAHN, O'BRIEN, CIAK, ALLISON and OLENICK, 1966; YIELDING, this
volume) that chloroquine forms a molecular complex with DNA and that quinine, like …

A technique for the electromagnetic analysis of physiological and patho-physiological states
in cell suspensions is presented. The technique is based upon high speed automatic …