… These data strongly imply the necessity for a negative charge at CK Surratt and GR Uhl, …
points of contact for incomingagonists and a CK Surratt, unpublished observations. Receptor " p …

With the breakthrough crystallization of the bacterial leucine transporter protein LeuT, the first
available X-ray structure for the neurotransmitter/sodium symporter family, development of …

The West African iboga plant has been used for centuries by the Bwiti and Mbiri tribes to
induce hallucinations during religious ceremonies. Ibogaine, the principal alkaloid responsible …

Hundreds of millions of US dollars are invested in the research and development of a single
drug. Lead compound development is an area ripe for new design strategies. Therapeutic …

Pharmacological and behavioral studies indicate that binding of cocaine and the amphetamines
by the dopamine transporter (DAT) protein is principally responsible for initiating the …

Ternary complexes of RNA polymerase, bearing the nascent RNA transcript, are intermediates
in the synthesis of all RNAs and are regulatory targets of factors that control RNA chain …

… The point mutant receptor T/S-3A was generated following the procedure described by
Surratt and colleagues ( 26) and stably expressed in CHO cell using the procedure described …

Departments of Chemistry and Biology, University of Virginia, Charlottesville, Virginia 22901
Received January 6, 1989; Revised Manuscript Received February 28, 1989 abstract: …

The μ-opioid receptor is the principal site of action in the brain by which morphine, other
opiate drugs of abuse, and endogenous opioid peptides effect analgesia and alter mood. A …

Objective To assess PharmD students' perceptions of the usefulness of Duquesne University's
Teaching Effectiveness Questionnaire (TEQ), the instrument currently employed for …