Nitric oxide signaling in the central nervous system
J Garthwaite, CL Boulton - Annual review of physiology, 1995 - annualreviews.org
Nitric oxide (NO) was first recognized as a messenger molecule in the central nervous system
(eNS) in 1988 (52), when it was identified as the unstable intercellular factor that had been …
(eNS) in 1988 (52), when it was identified as the unstable intercellular factor that had been …
[PDF][PDF] Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1, 2, 4] oxadiazolo [4, 3-a] quinoxalin-1-one.
J Garthwaite, E Southam, CL Boulton, EB Nielsen… - Molecular …, 1995 - Citeseer
In brain and other tissues, nitric oxide (NO) operates as a diffusible second messenger that
stimulates the soluble form of the guanylyl cyclase enzyme and so elicits an accumulation of …
stimulates the soluble form of the guanylyl cyclase enzyme and so elicits an accumulation of …
FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant …
…, JL Kutok, IR Williams, CL Boulton… - Blood, The Journal …, 2002 - ashpublications.org
FLT3 receptor tyrosine kinase is expressed on lymphoid and myeloid progenitors in the
hematopoietic system. Activating mutations in FLT3 have been identified in approximately 30% …
hematopoietic system. Activating mutations in FLT3 have been identified in approximately 30% …
PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model
…, JL Kutok, IR Williams, CL Boulton… - Proceedings of the …, 2002 - National Acad Sciences
Acute promyelocytic leukemia (APL) cells invariably express aberrant fusion proteins involving
the retinoic acid receptor α (RARα). The most common fusion partner is promyelocytic …
the retinoic acid receptor α (RARα). The most common fusion partner is promyelocytic …
[PDF][PDF] CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML)
LM Kelly, JC Yu, CL Boulton, M Apatira, J Li… - Cancer cell, 2002 - cell.com
Up to 30% of acute myelogenous leukemia (AML) patients harbor an activating internal tandem
duplication (ITD) within the juxtamembrane domain of the FLT3 receptor, suggesting that …
duplication (ITD) within the juxtamembrane domain of the FLT3 receptor, suggesting that …
Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase
CL Boulton, E Southam, J Garthwaite - Neuroscience, 1995 - Elsevier
The diffusible second messenger, nitric oxide, is synthesised in central neurons in response
to activation of glutamate receptors or other stimuli that increase cytosolic Ca 2+ …
to activation of glutamate receptors or other stimuli that increase cytosolic Ca 2+ …
[PDF][PDF] PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease
J Cools, EH Stover, CL Boulton, J Gotlib, RD Legare… - Cancer cell, 2003 - cell.com
FIP1L1-PDGFRα causes hypereosinophilic syndrome (HES) and is inhibited by the tyrosine
kinase inhibitor imatinib (Gleevec). Imatinib is a potent inhibitor of ABL, ARG, PDGFRα, …
kinase inhibitor imatinib (Gleevec). Imatinib is a potent inhibitor of ABL, ARG, PDGFRα, …
Effect of intrawound vancomycin powder in operatively treated high-risk tibia fractures: a randomized clinical trial
…, C Caroom, MD Jenkins, CL Boulton… - JAMA …, 2021 - jamanetwork.com
Importance Despite the widespread use of systemic antibiotics to prevent infections in
surgically treated patients with fracture, high rates of surgical site infection persist. Objective To …
surgically treated patients with fracture, high rates of surgical site infection persist. Objective To …
Spontaneous X chromosome MI and MII nondisjunction events in Drosophila melanogaster oocytes have different recombinational histories
KE Koehler, CL Boulton, HE Collins, RL French… - Nature …, 1996 - nature.com
Recent studies of human oocytes have demonstrated an enrichment for distal exchanges
among meiosis I (MI) nondisjunction events and for proximal exchanges among meiosis II (MII) …
among meiosis I (MI) nondisjunction events and for proximal exchanges among meiosis II (MII) …
Intramedullary cannulated headless screw fixation of a comminuted subcapital metacarpal fracture: case report
CL Boulton, M Salzler, CS Mudgal - The Journal of hand surgery, 2010 - Elsevier
This case report describes an alternative technique for the fixation of displaced comminuted
subcapital fractures of the metacarpal with limited distal bone stock. Using a cannulated …
subcapital fractures of the metacarpal with limited distal bone stock. Using a cannulated …