Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity

D Gao, DL Narasimhan, J Macdonald, R Brim… - Molecular …, 2009 - ASPET
Enhancing cocaine metabolism by administration of cocaine esterase (CocE) has been
recognized as a promising treatment strategy for cocaine overdose and addiction, because …

Anti-cocaine compositions and treatment

…, D Gao, JH Woods, RK Sunahara, DL Narasimhan… - uknowledge.uky.edu
Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics.
Specifically, some embodiments of the invention relate to highly efficient, thermostable, and …

Video laryngoscopy is associated with increased first pass success and decreased rate of esophageal intubations during urgent endotracheal intubation in a medical …

…, SJ Koenig, M Narasimhan… - Journal of intensive …, 2015 - journals.sagepub.com
… The rate of esophageal intubations in our study when using the DL is higher than that … in
using the DL. The higher rate in our report reflects a relative inexperience in the use of DL by the …

[HTML][HTML] COVID-19: Poor outcomes in patients with zinc deficiency

…, S Manoharan, V Ramani, G Narasimhan… - International Journal of …, 2020 - Elsevier
Background Zinc is a trace element with potent immunoregulatory and antiviral properties,
and is utilized in the treatment of coronavirus disease 2019 (COVID-19). However, we do not …

Severe Jaundice in a COVID-19 Patient–Virus or Drug?

…, V Patil, D Sachan, G Narasimhan… - Journal of Clinical …, 2021 - jcehepatology.com
… , AST 36 U/L, ALT 41 U/L, ALP 298 U/L, GGT 243 U/L, Albumin 3.9 mg/dl and INR 1.2. His
abdominal ultrasound showed mild hepatomegaly with no features of chronic liver disease. …

Neural rgb (r) d sensing: Depth and uncertainty from a video camera

C Liu, J Gu, K Kim, SG Narasimhan… - Proceedings of the …, 2019 - openaccess.thecvf.com
… In this paper, we present a DL-based method for continuous depth sensing from a monocular
video camera. Our method estimates a depth probability distribution volume from a local …

Correlation of breath ammonia with blood urea nitrogen and creatinine during hemodialysis

LR Narasimhan, W Goodman… - Proceedings of the …, 2001 - National Acad Sciences
dl and whose postdialysis BUN is 30 mg/dl. A second example involves a predialysis BUN of
200 mg/dl and a postdialysis BUN of 60 mg/dl… stays above 60 mg/dl for long periods of time. …

Deep learning models for water stage predictions in south florida

…, A John, J Obeysekera, A Leon, G Narasimhan - arXiv preprint arXiv …, 2023 - arxiv.org
… Besides, a DL model combing recurrent neural networks (RNN) and convolutional neural …
other DL models in our paper. Compared to physics-based models, the surrogate DL models …

Medium-throughput drug screening of patient-derived organoids from colorectal peritoneal metastases to direct personalized therapy

V Narasimhan, JA Wright, M Churchill, T Wang… - Clinical Cancer …, 2020 - AACR
Purpose: Patients with colorectal cancer with peritoneal metastases (CRPMs) have limited
treatment options and the lowest colorectal cancer survival rates. We aimed to determine …

[BOOK][B] Alteration of Rep functions by phosphatase inhibition and interaction of adeno-associated virus with different papillomavirus clones

DL Narasimhan - 2001 - search.proquest.com
Adeno-associated virus Rep proteins are multi-functional proteins. They are essential for AAV
DNA replication, AAV gene expression, site specific integration, and rescue of the provirus …