Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases

T Ishizaki, M Uehata, I Tamechika, J Keel… - Molecular …, 2000 - ASPET
… 1C) with about 10 times higher affinities, the K i values being 0.03 μM for ROCK-I and 0.05
i values for two other Rho effector kinases, citron kinase and PKN, as well as PKCα. TheK i

WF‐536 inhibits metastatic invasion by enhancing the host cell barrier and inhibiting tumour cell motility

M Nakajima, K Katayama, I Tamechika… - Clinical and …, 2003 - Wiley Online Library
… The major findings of the present study are as follows: (i) Wf-536 showed potent and
selective inhibitory activity against ROCK, which was superior to that of Y-27632; (ii) Wf-536 …

[HTML][HTML] Accelerated Evolution in Inhibitor Domains of Porcine Elafin Family Members (∗)

I Tamechika, M Itakura, Y Saruta, M Furukawa… - Journal of Biological …, 1996 - ASBMB
Through the analysis of the porcine gene encoding the elastase inhibitor elafin, we
demonstrated that there are at least three closely related members of the elafin family, and their …

[HTML][HTML] Cloning, Characterization, and Tissue Distribution of Porcine SPAI, a Protein with a Transglutaminase Substrate Domain and the WAP Motif (∗)

…, T Hosoya, M Itakura, S Hirose, I Tamechika… - Journal of Biological …, 1995 - ASBMB
The primary and gene structures and tissue distribution of porcine SPAI-2, a protein that
belongs to the WAP protein superfamily and has a sodium-potassium ATPase inhibitory activity, …

Discovery of a new type of proteinase inhibitor family whose members have an anchoring sequence

S Hirose, M Furukawa, I Tamechika, M Itakura… - Intracellular Protein …, 1996 - Springer
A large number of proteolytic systems are assembled in our body and their activities are strictly
regulated by a delicate balance between the production, activation, and inhibition of the …

Investigation of single sideband optical lithography using oblique incidence illumination

E Tamechika, S Matsuo, K Komatsu… - Journal of Vacuum …, 1992 - pubs.aip.org
We propose a new method for enhancing the image contrast in oblique illumination lithography.
In this article, we analyze the modulation transfer function to clarify the cause of poor …

Outdoor performance of triple stacked a-Si photovoltaic module in various geographical locations and climates

K Fukae, CC Lim, M Tamechika… - … Record of the …, 1996 - ieeexplore.ieee.org
… A-Si-I showed stabilization after 1000 to 2000 hours resulted in 22% degradation (see Fig.1).
A-Si-2 and a-Si-3 showed 15% and 18% saturated degradation respectively. IV …

Analytical method for image characteristics of annular illumination with a spatial filter in optical projection lithography

Y Takeuchi, S Matsuo, ETE Tamechika… - Japanese journal of …, 1992 - iopscience.iop.org
… In the following, we will show that the intensity I from the … I have peaks near the edges and
contribute to the image deformations. If I is symmetrically distributed, the total intensity I will be …

First experience with Belle II Aerogel RICH detector

…, L Šantelj, T Sumiyoshi, M Tabata, S Tamechika… - Nuclear Instruments and …, 2019 - Elsevier
… as (1) ϵ K ∕ π → K = N s i g , p a s s N s i g , a l l , where N s i g , a l l is the number of signal
events, when negative (positive) particle enters ARICH, and N s i g , p a s s is its subsample …

Ischemic colitis in a 33-year-old woman on danazol treatment for endometriosis.

T Miyata, Y Tamechika… - American Journal of …, 1988 - search.ebscohost.com
I). Previous operations included surgery for a right ovarian cyst 6 yr before, and a left adrenaiectomy
4 yr before, under a diagnosis of primary aldosteronism. There was no history of …