Transcription switches for protoxylem and metaxylem vessel formation

M Kubo, M Udagawa, N Nishikubo… - Genes & …, 2005 - genesdev.cshlp.org
… Sundberg for providing the poplar hybrid aspen; SIGnAL, ABRC, and GABI-Kat for providing
T-DNA insertion lines; and M. Ohme-Takagi for useful advice on the dominant repression …

SOCS proteins, cytokine signalling and immune regulation

A Yoshimura, T Naka, M Kubo - Nature Reviews Immunology, 2007 - nature.com
Suppressor of cytokine signalling (SOCS) proteins are inhibitors of cytokine signalling pathways.
Studies have shown that SOCS proteins are key physiological regulators of both innate …

Suppressors of cytokine signaling and immunity

M Kubo, T Hanada, A Yoshimura - Nature immunology, 2003 - nature.com
The suppressors of cytokine signaling (SOCS) and cytokine-inducible SH2 protein are key
physiological regulators of the immune system. Principally, SOCS1 and SOCS3 regulate T …

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

…, E Agerbo, M Al Eissa, M Albus, M Alexander… - Nature, 2022 - nature.com
Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Colorimetric chiral recognition by a molecular sensor

Y Kubo, S Maeda, S Tokita, M Kubo - Nature, 1996 - nature.com
… etherification in the presence of a base, tosylation with tosyl chloride, a modified
Williamson synthesis with calix[4]arene" in the presence of base, and a condensation with 4-amino-m-…

Genetics of rheumatoid arthritis contributes to biology and drug discovery

…, EW Karlson, A Taniguchi, R Yamada, M Kubo… - Nature, 2014 - nature.com
… When one phenotype had n loci of which m loci were in region-based pleiotropy with RA, we
obtained a null distribution of m by randomly selecting n SNPs from obtained NHGRI GWAS …

A cross-population atlas of genetic associations for 220 human phenotypes

…, G Tamiya, M Yamamoto, Y Nakamura, M Kubo… - Nature …, 2021 - nature.com
… size N × K whose columns are phenotype singular vectors, S is a diagonal matrix of size K
× K whose elements are singular values and V = (v j,k ) j,k is an orthonormal matrix of size M × …

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

…, BZ Alizadeh, M Parkes, T BK, MJ Daly, M Kubo… - Nature …, 2015 - nature.com
Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

…, M Koromina, TM Kranz, HR Kranzler, M Kubo… - Nature …, 2021 - nature.com
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide
association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Nanometre-scale thermometry in a living cell

G Kucsko, PC Maurer, NY Yao, M Kubo, HJ Noh, PK Lo… - Nature, 2013 - nature.com
… the transition frequency (Δ) between the |m s = 0> and |m s = ±1> states (m s , spin projection)
has a … measurements where the spin is prepared with m s = 0 and, respectively, m s = −1. …