In previous studies we have demonstrated that transforming growth factor (TGF)-α/c-myc
double transgenic mice exhibit an enhanced rate of cell proliferation, accumulate extensive …

Background The role of adjuvant radiotherapy for high-risk cutaneous squamous cell
carcinomas after surgery with negative margins is unclear. Objective To conduct a systematic …

Deregulation of E2F transcriptional control has been implicated in oncogenic transformation.
Consistent with this idea, we recently demonstrated that during hepatocarcinogenesis in c-…

Polyacrylamide gel electrophoresis is a reliable and widely used technique for the separation,
identification and characterization of proteins and protein mixtures. With the introduction of …

Aflatoxin B 1 has been suggested as a causative agent for a G to T mutation at codon 249 in
the p53 gene in human hepatocellular carcinomas (HCC) from southern Africa and Qidong …

Animal thioredoxin reductases (TRs) are selenocysteine-containing flavoenzymes that utilize
NADPH for reduction of thioredoxins and other protein and nonprotein substrates. Three …

Two‐dimensional gel electrophoresis with subsequent analysis by mass spectrometry was
applied to study differences in protein expression between benign and malignant solid …

Aflatoxin B 1 has been suggested as a causative agent for a G to T mutation at codon 249 in
the p53 gene in human bepatocellular carcinomas from southern Africa and Quidong in …

Pathways for the cytochrome P-450 monooxygenase-mediated covalent binding of furosemide
to microsomal protein were examined. Two pathways were considered: one leading to a …

The mutageicity of phenacetin and acetaminophen and their respective N-hydroxylated
metabolites was determined in Salmonella typhimurium tester strains TA 98 and TA 100 in both …