… Seydoux, JP Giacobino & P Muzzin P, unpublished observations) and skeletal muscle (42,
and O Boss, H Ghezraoui, J Seydoux, JP Giacobino & P Muzzin P, unpublished observations) …

Glucocorticoids are important hormones in the regulation of metabolic homeostasis. We
infused normal rats with dexamethasone given intracerebroventricularly (icv) for 3 days. This …

… P. Effect of endurance training on mRNA expression of uncoupling proteins 1, 2, and 3 in …
t test was used to determine statistical significance, which was accepted at the P õ 0.05 level. …

… A: Autoradiogram of a Northern blot of various human tissue poly(A) RNA hybridized with
a 32 P-labeled human UCP2 probe consisting of the full-length UCP2 cDNA. The molecular …

… = NS) and UCP1 (117.2% ± 33.3% of control; values normalized by cyclophilin A, used as a
reporter gene; P = … A 2-tailed P value less than 0.05 was considered statistically significant. …

Clones encoding an atypical beta-adrenergic receptor were isolated from a rat brown
adipose tissue cDNA library. This receptor expressed in Chinese hamster ovary (CHO) cells …

… Cell proteins (30 μg) were subjected to electrophoresis on a 12% polyacrylamide gel then
electrotransfered to an Immobilon P membrane (Millipore), blocked with 0.5% nonfat dry milk …

… detection of UCP1 was performed as follows: (a) 0.3% hydrogen peroxide in methanol for
30 min to inactivate endogenous peroxidase; (b) normal rabbit serum 1 : 75 in NaCl/P i for 20 …

Catecholamines are viewed as major stimulants of diet- and cold-induced thermogenesis
and of fasting-induced lipolysis, through the β-adrenoceptors (β 1 /β 2 /β 3 ). To test this …

The ob/ob mouse is genetically deficient in leptin and exhibits both an obese and a mild non-insulin-dependent
diabetic phenotype. To test the hypothesis that correction of the obese …