T-helper cells that produce interleukin-17 (T H 17 cells) are a recently identified CD4 + T-cell
subset with characterized pathological roles in autoimmune diseases 1 , 2 , 3 . The nuclear …

Cross-coupling chemistry is widely applied to carbon-carbon bond formation in the
synthesis of medicines, agrochemicals, and other functional materials. Recently, single-electron–…

The retinoic acid receptor-related receptors (RORs) are members of the nuclear receptor (NR)
superfamily of transcription factors. Several NRs are still characterized as orphan …

… Reaction energetics were calculated with DFT by using B3LYP/6–311++G(2d,2p)-CPCM(MeOH)
for all atoms, except iodine where the basis set LanL2DZ with additional p-diffuse and d…

Several nuclear receptors (NRs) are still character-ized as orphan receptors because ligands
have not yet been identified for these proteins. The retinoic acid receptor-related receptors (…

A nontoxic and inexpensive photocatalytic initiation of anti-Markovnikov hydrothiolation of
olefins using visible light is reported. This method is characterized by low catalyst loading, …

The Chan–Lam reaction remains a highly utilized transformation for C–N bond formation.
However, anilines remain problematic substrates due to their lower nucleophilicity. To address …

The enantioselective synthesis of acyclic all-carbon quaternary centers remains a significant
challenge in organic synthesis.[1] In view of the tremendous utility of enantioselective aldol …

Conditions were found for the successful Effenberger α,α‘-annulation of 3,3-dimethyl-2,4,6-triprenyl
cyclohexanone silyl enol ethers with malonyl chloride to give the corresponding …

C–H functionalization of electron-deficient heteroarenes using commercial unactivated alkyl
halides through reductive quenching photoredox catalysis was developed. Mainstream …