Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing
…, E LeCluyse, HJ Clewell, RS Thomas… - Toxicological …, 2015 - academic.oup.com
We previously integrated dosimetry and exposure with high-throughput screening (HTS) to
enhance the utility of ToxCast HTS data by translating in vitro bioactivity concentrations to …
enhance the utility of ToxCast HTS data by translating in vitro bioactivity concentrations to …
The next generation blueprint of computational toxicology at the US Environmental Protection Agency
RS Thomas, T Bahadori, TJ Buckley… - Toxicological …, 2019 - academic.oup.com
The US Environmental Protection Agency (EPA) is faced with the challenge of efficiently
and credibly evaluating chemical safety often with limited or no available toxicity data. The …
and credibly evaluating chemical safety often with limited or no available toxicity data. The …
Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework
RS Thomas, MA Philbert, SS Auerbach… - toxicological …, 2013 - academic.oup.com
Based on existing data and previous work, a series of studies is proposed as a basis toward
a pragmatic early step in transforming toxicity testing. These studies were assembled into a …
a pragmatic early step in transforming toxicity testing. These studies were assembled into a …
ToxCast chemical landscape: paving the road to 21st century toxicology
…, SB Little, KM Crofton, RS Thomas - Chemical research in …, 2016 - ACS Publications
The US Environmental Protection Agency’s (EPA) ToxCast program is testing a large library
of Agency-relevant chemicals using in vitro high-throughput screening (HTS) approaches to …
of Agency-relevant chemicals using in vitro high-throughput screening (HTS) approaches to …
Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice
…, RS Thomas, RS McCuskey… - Proceedings of the …, 2000 - National Acad Sciences
A physiological examination of mice harboring a null allele at the aryl hydrocarbon (Ah) locus
revealed that the encoded aryl hydrocarbon receptor plays a role in the resolution of fetal …
revealed that the encoded aryl hydrocarbon receptor plays a role in the resolution of fetal …
Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment
…, RJ Kavlock, AM Richard, RS Thomas - Toxicological …, 2012 - academic.oup.com
High-throughput in vitro toxicity screening can provide an efficient way to identify potential
biological targets for chemicals. However, relying on nominal assay concentrations may …
biological targets for chemicals. However, relying on nominal assay concentrations may …
Shareholder proposals in the new millennium: Shareholder support, board response, and market reaction
RS Thomas, JF Cotter - Journal of corporate finance, 2007 - Elsevier
Although the owners of publicly traded companies have had the right to offer shareholder
proposals using Rule 14a-8 for several decades, the effectiveness of the rule has been …
proposals using Rule 14a-8 for several decades, the effectiveness of the rule has been …
Realigning corporate governance: Shareholder activism by labor unions
SJ Schwab, RS Thomas - Mich. L. Rev., 1997 - HeinOnline
… These are discussed in more detail in Thomas & Martin, supra note 6 (manuscript at 19
n34)… For further discussion of labor activism in the 1994 proxy season, see Thomas & Martin, …
n34)… For further discussion of labor activism in the 1994 proxy season, see Thomas & Martin, …
Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening
Many chemicals in commerce today have undergone limited or no safety testing. To reduce
the number of untested chemicals and prioritize limited testing resources, several …
the number of untested chemicals and prioritize limited testing resources, several …
The new look of shareholder litigation: Acquisition-oriented class actions
RB Thompson, RS Thomas - Vand. L. Rev., 2004 - HeinOnline
… The older vintage, including a study by Professor Thomas Jones analyzing shareholder
litigation in the 197178 period95 and one by Professor Roberta Romano analyzing shareholder …
litigation in the 197178 period95 and one by Professor Roberta Romano analyzing shareholder …