Polyol recognition by a steroid-capped porphyrin. Enhancement and modulation of misfit guest binding by added water or methanol

RP Bonar-Law, JKM Sanders - Journal of the American Chemical …, 1995 - ACS Publications
A spacious semisynthetic receptor composed of a zinc porphyrin bridged by a steroidal diol
is shown to complex alcohols and polyols in nonpolar solvents by a combination of Lewis …

Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex

…, PA Stocks, B Meunier, DP Williams, R Bonar-Law… - Molecular …, 2008 - ASPET
The development of drug resistance to affordable drugs has contributed to a global increase
in the number of deaths from malaria. This unacceptable situation has stimulated research …

Candidate Selection and Preclinical Evaluation of N-tert-Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century

…, PA Winstanley, A Mukhtar, R Bonar-Law… - Journal of medicinal …, 2009 - ACS Publications
N-tert-Butyl isoquine (4) (GSK369796) is a 4-aminoquinoline drug candidate selected and
developed as part of a public−private partnership between academics at Liverpool, MMV, and …

Porphyrin synthesis in surfactant solution: Multicomponent assembly in micelles

RP Bonar-Law - The Journal of Organic Chemistry, 1996 - ACS Publications
A synthesis of meso-substituted porphyrins in anionic sodium dodecyl sulfate micelles has
been developed. Polar, functionalized aromatic aldehydes condense reversibly with pyrrole …

Towards synthetic enzymes based on porphyrins and steroids

RP Bonar-Law, LG Mackay, CJ Walter… - Pure and applied …, 1994 - degruyter.com
R. P. BONAR-LAW eta/. … f-3 -r 7 PH …

Artificial receptors for carbohydrate derivatives

RP BonarLaw, AP Davis… - … International Edition in …, 1990 - Wiley Online Library
There is widespread interest in the recognition and binding of neutral, polar molecules in
organic solvents. Particular attention has been paid to derivatives of amino acids [’] and …

'Living'macrolactonisation: thermodynamically-controlled cyclisation and interconversion of oligocholates

PA Brady, RP Bonar-Law, SJ Rowan… - Chemical …, 1996 - pubs.rsc.org
Bonar-Law, Stuart J. Rowan, Christopher J. Suckling and Jeremy KM Sanders* … RP
Bonar-Law and JKM Sanders, Tetrahedron Lett., 1992, 33, 207 1. RP Bonar-Law, LG …

Dinuclear complexes as connectors for carboxylates. Self-assembly of a molecular box

RP Bonar-Law, TD McGrath, N Singh… - Chemical …, 1999 - pubs.rsc.org
Bonar-Law,* Thomas D. McGrath, Nirmal Singh, Jamie F. Bickley and Alexander Steiner …
A very recent report12 by Cotton and Murillo et al. on diacid-linked Rh2 and Mo2 …

Cholic acid as an architectural component in biomimetic/molecular recognition chemistry; synthesis of the first “cholaphanes”.

RP Bonar-Law, AP Davis - Tetrahedron, 1993 - Elsevier
The readily available steroid cholic acid (1) has several advantages as a precursor for
extended, preorganised molecular frameworks. In the present work, full details are given for the …

Dirhodium (II) carboxylate complexes as building blocks. Synthesis and structures of square boxes with tilted walls

JF Bickley, RP Bonar-Law, C Femoni… - Journal of the …, 2000 - pubs.rsc.org
… A total of 10115 unique reflections were measured and used in the refinement, which
converged to R = 0.0628 for the reflections with F [hair space] 2 … A total of 11047 unique …