User profiles for S. J. Wort

Stephen John Wort

Verified email at rbht.nhs.uk
Cited by 14600

[HTML][HTML] Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review

LC Price, SJ Wort, SJ Finney, PS Marino, SJ Brett - Critical Care, 2010 - Springer
Introduction Pulmonary vascular dysfunction, pulmonary hypertension (PH), and resulting
right ventricular (RV) failure occur in many critical illnesses and may be associated with a …

Inflammation in pulmonary arterial hypertension

LC Price, SJ Wort, F Perros, P Dorfmüller, A Huertas… - Chest, 2012 - Elsevier
… Financial/nonfinancial disclosures: The authors have reported to CHEST the following
conflicts of interest: Dr Wort has relationships with Actelion, Bayer Schering, GSK, Novartis, and …

The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension

D Shao, JES Park, SJ Wort - Pharmacological Research, 2011 - Elsevier
The term pulmonary arterial hypertension (PAH) describes a rare group of diseases
characterized by raised pulmonary vascular resistance, resulting from vascular remodelling in the …

Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United …

…, JL Lordan, S Gaine, JG Coghlan, SJ Wort… - American journal of …, 2012 - atsjournals.org
Rationale: Incident pulmonary arterial hypertension was underrepresented in most pulmonary
hypertension registries and may have a different disease profile to prevalent disease. …

Survival prospects and circumstances of death in contemporary adult congenital heart disease patients under follow-up at a large tertiary centre

…, L Swan, A Uebing, W Li, S Babu-Narayan, SJ Wort… - Circulation, 2015 - Am Heart Assoc
Background— Adult congenital heart disease (ACHD) patients have ongoing morbidity and
reduced long-term survival. Recently, the importance of specialized follow-up at tertiary …

Pulmonary angiopathy in severe COVID-19: physiologic, imaging, and hematologic observations

…, S Trenfield, R Trimlett, C Weaver, SJ Wort… - American journal of …, 2020 - atsjournals.org
Rationale: Clinical and epidemiologic data in coronavirus disease (COVID-19) have accrued
rapidly since the outbreak, but few address the underlying pathophysiology. Objectives: To …

Improved survival among patients with Eisenmenger syndrome receiving advanced therapy for pulmonary arterial hypertension

…, S Goletto, G Giannakoulas, L Swan, SJ Wort… - Circulation, 2010 - Am Heart Assoc
Background— Advanced therapy (AT) for pulmonary arterial hypertension in the context of
congenital heart disease (Eisenmenger syndrome) improves pulmonary hemodynamics, …

Dynamic risk stratification of patient long-term outcome after pulmonary endarterectomy: results from the United Kingdom National Cohort

…, B Schreiber, G Coghlan, K Dimopoulos, SJ Wort… - Circulation, 2016 - Am Heart Assoc
… Dr Wort has received speaker fees and honoraria from Actelion and Pfizer, has received
research grants from Actelion, Pfizer, and Bayer, and is on advisory boards for Pfizer, GSK, …

Thrombosis and COVID-19 pneumonia: the clot thickens!

…, C McCabe, B Garfield, SJ Wort - European Respiratory …, 2020 - Eur Respiratory Soc
Wort … Conflict of interest: SJ Wort reports grants and personal fees from Actelion
Pharmaceuticals and Bayer, personal fees from MSD and GSK, outside the submitted work. …

[HTML][HTML] Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

…, Q Waisfisz, J Wharton, SJ Wort… - Nature …, 2018 - nature.com
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious
variation within components of the transforming growth factor-β pathway, particularly the …