Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial
…, F Wenz, S Post, A Matzdorff, S Laechelt… - The lancet …, 2012 - thelancet.com
Background Fluorouracil-based chemoradiotherapy is regarded as a standard perioperative
treatment in locally advanced rectal cancer. We investigated the efficacy and safety of …
treatment in locally advanced rectal cancer. We investigated the efficacy and safety of …
MicroRNA profiling in K-562 cells under imatinib treatment: influence of miR-212 and miR-328 on ABCG2 expression
E Turrini, S Haenisch, S Laechelt… - Pharmacogenetics …, 2012 - journals.lww.com
… Luciferase activities were determined with the Dual Luciferase Reporter Assay System (Promega,
Madison, Wisconsin, USA) 48 h after transfection according to the manufacturer’s …
Madison, Wisconsin, USA) 48 h after transfection according to the manufacturer’s …
Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379
S Haenisch, S Laechelt, H Bruckmueller, A Werk… - Molecular …, 2011 - ASPET
microRNAs (miRNAs), which contribute to the post-transcriptional processing through 3′-untranslated
region-interference, have been shown to be involved in the regulation of ATP-…
region-interference, have been shown to be involved in the regulation of ATP-…
Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function
S Laechelt, E Turrini, A Ruehmkorf… - The …, 2011 - nature.com
ABCC2 (MRP2) is an important export pump, expressed at tissue barriers. The genetic
variants− 24C> T, 1249G> A and 3972C> T are leading to inter-individual differences of …
variants− 24C> T, 1249G> A and 3972C> T are leading to inter-individual differences of …
Capecitabine (Cape) versus 5-fluorouracil (5-FU)–based (neo) adjuvant chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC): Long-term results of a …
…, FK Wenz, S Post, A Matzdorff, S Laechelt… - Journal of Clinical …, 2011 - ascopubs.org
3504 Background: 5-FU based CRT is regarded standard perioperative treatment in LARC.
We report long-term data of a non-inferiority phase III trial investigating (neo-)adjuvant CRT …
We report long-term data of a non-inferiority phase III trial investigating (neo-)adjuvant CRT …
Capecitabine (Cape) versus 5-fluorouracil (5-FU)-based (neo-) adjuvant chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC): safety results of a …
…, F Wenz, S Post, A Matzdorff, S Laechelt… - Journal of Clinical …, 2009 - ascopubs.org
4014 Background: 5-FU based CRT is regarded standard perioperative treatment in LARC.
Here we report safety data of a non-inferiority phase III trial investigating (neo-)adjuvant CRT …
Here we report safety data of a non-inferiority phase III trial investigating (neo-)adjuvant CRT …
Women and the social economy
A Chevreau, N Laechelt - 2023 - oecd-ilibrary.org
… perceived as “women’s jobs or roles”. After analysing women’s employment in the social …
It also suggests ways to increase women’s participation in high-growth sectors within the …
It also suggests ways to increase women’s participation in high-growth sectors within the …
Glycemic control and urinary tract infections in women with type 1 diabetes: results from the DCCT/EDIC
…, M Johnson, K Gunyou, L Thomas, J Laechelt… - The Journal of …, 2016 - Elsevier
… , markers of diabetes control, treatment and diabetic complications were compared by
UTI and HbA1c status at EDIC year 17 using the chi-square test for categorical variables (Fisher’s …
UTI and HbA1c status at EDIC year 17 using the chi-square test for categorical variables (Fisher’s …
Joining Forces for Gender Equality: Women and the social economy
A Chevreau, N Laechelt - 2023 - policycommons.net
… perceived as “women’s jobs or roles”. After analysing women’s employment in the social …
It also suggests ways to increase women’s participation in high-growth sectors within the …
It also suggests ways to increase women’s participation in high-growth sectors within the …
Induction of influx and efflux transporters and cytochrome P450 3A4 in primary human hepatocytes by rifampin, rifabutin, and rifapentine
B Williamson, KE Dooley, Y Zhang… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Rifampin is a potent inducer of cytochrome P450 (CYP) enzymes and transporters. Drug-drug
interactions during tuberculosis treatment are common. Induction by rifapentine and …
interactions during tuberculosis treatment are common. Induction by rifapentine and …