Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation
of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis …

Multiple roles of reactive oxygen species (ROS) and their consequences for health and
disease are emerging throughout biological sciences. This development has led researchers …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are closely linked to
degenerative diseases such as Alzheimer’s disease, Parkinson’s, neuronal death including …

Ferroptosis is a non-apoptotic form of cell death induced by small molecules in specific tumour
types, and in engineered cells overexpressing oncogenic RAS. Yet, its relevance in non-…

… A detailed analysis of potentially oxidized phospholipids generated during ferroptosis is
described in this issue by Kagan et al. , who show that AA- and adrenic acid (AdA)-containing …

Enigmatic lipid peroxidation products have been claimed as the proximate executioners of
ferroptosis—a specialized death program triggered by insufficiency of glutathione peroxidase …

Single-walled carbon nanotubes (SWCNT) are new materials of emerging technological
importance. As SWCNT are introduced into the life cycle of commercial products, their effects on …

Programmed death (apoptosis) is turned on in damaged or unwanted cells to secure their
clean and safe self-elimination. The initial apoptotic events are coordinated in mitochondria, …

Recognition of injured mitochondria for degradation by macroautophagy is essential for
cellular health, but the mechanisms remain poorly understood. Cardiolipin is an inner …

We have shown previously that single-walled carbon nanotubes can be catalytically biodegraded
over several weeks by the plant-derived enzyme, horseradish peroxidase 1 . However, …