Cobalamin and folate deficiency: acquired and hereditary disorders in children.
DS Rosenblatt, VM Whitehead - Seminars in hematology, 1999 - europepmc.org
This review highlights the features of cobalamin and folate deficiency and insufficiency that
are particular to children. Maternal deficiency of cobalamin and insufficiency or deficiency of …
are particular to children. Maternal deficiency of cobalamin and insufficiency or deficiency of …
Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization
TA Garrow, AA Brenner, VM Whitehead… - Journal of Biological …, 1993 - ASBMB
Human cDNAs for cytosolic and mitochondrial serine hydroxymethyltransferase (SHMT)
were cloned by functional complementation of an Escherichia coli glyA mutant with a human …
were cloned by functional complementation of an Escherichia coli glyA mutant with a human …
Megaloblastic anemia
D Watkins, VM Whitehead… - Nathan and Oski's …, 2008 - books.google.com
Before the mid-1920s, pernicious anemia was a disease dreaded as much as drug-resistant
leukemia is today. With its characteristic megaloblastic bone marrow, pernicious anemia …
leukemia is today. With its characteristic megaloblastic bone marrow, pernicious anemia …
Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute …
VM Whitehead, MJ Vuchich, SJ Lauer, D Mahoney… - 1992 - ashpublications.org
Hyperdiploidy (greater than 50 chromosomes, or a DNA index greater than 1.16) confers a
favorable prognosis in B-lineage acute lymphoblastic leukemia of childhood. Children with B-…
favorable prognosis in B-lineage acute lymphoblastic leukemia of childhood. Children with B-…
[HTML][HTML] Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic …
VM Whitehead, DS Rosenblatt, MJ Vuchich, JJ Shuster… - Blood, 1990 - Elsevier
Lymphoblasts in bone marrow samples, obtained from 43 children with acute lymphoblastic
leukemia at diagnosis, were incubated with 1.0 μmol/L ( 3 H] methotrexate for 24 hours in …
leukemia at diagnosis, were incubated with 1.0 μmol/L ( 3 H] methotrexate for 24 hours in …
A certain exact sequence
JHC Whitehead - Annals of Mathematics, 1950 - JSTOR
… BY JHC WHITEHEAD … 54 JHC WHITEHEAD … Many of these facts have been
recorded by GW Whitehead in f23]. In particular his results may be used to show that, if 2 = Z(K) …
recorded by GW Whitehead in f23]. In particular his results may be used to show that, if 2 = Z(K) …
Prolonged inhibition of DNA synthesis associated with the accumulation of methotrexate polyglutamates by cultured human cells
DS Rosenblatt, VM Whitehead, N Vera, A Pottier… - Molecular …, 1978 - ASPET
Incubation of cultured human fibroblasts in 1 µM methotrexate results in a progressive
accumulation of poly-γ-glutamyl derivatives. This accumulation is not dependent on new protein …
accumulation of poly-γ-glutamyl derivatives. This accumulation is not dependent on new protein …
Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute …
VM Whitehead, MJ Vuchich, LD Cooley… - Leukemia & …, 1998 - Taylor & Francis
Levels of accumulation of methotrexate polyglutamates were measured in vitro in lymphoblasts
obtained at diagnosis from children with B-progenitor cell acute lymphoblastic leukemia (…
obtained at diagnosis from children with B-progenitor cell acute lymphoblastic leukemia (…
High glucocorticoid receptor content of leukemic blasts is a favorable prognostic factor in childhood acute lymphoblastic leukemia
…, J Boyett, JD Pullen, MJ Borowitz, VM Whitehead… - 1993 - ashpublications.org
We have previously shown that the number of glucocorticoid receptors (GR) per cell in
malignant lymphoblasts from children with newly diagnosed pre-B- and early pre-B-cell acute …
malignant lymphoblasts from children with newly diagnosed pre-B- and early pre-B-cell acute …
Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells
VM Whitehead - Cancer research, 1977 - AACR
The ability of L1210 mouse leukemia cells and of a mutant methotrexate-resistant cell line (L1210/MTX)
to synthesize methotrexate polyglutamates was studied. Host DBA/2 mice were …
to synthesize methotrexate polyglutamates was studied. Host DBA/2 mice were …