This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested, …

Serious side-effects caused by drug interactions have attracted a great deal of attention and
have become a social problem since the coadministration of ketoconazole and terfenadine …

Drug transporters are expressed in many tissues such as the intestine, liver, kidney, and brain,
and play key roles in drug absorption, distribution, and excretion. The information on the …

… Sohara, Y. Sugiyama and HM designed the overall project, and HM wrote the manuscript.
All authors discussed the results and commented on the manuscript. … Yukihiko Sugiyama …

… y be a small deviation from the steadystate flow of identical … After neglecting higher terms of
y, the linearized equation is … from the periodicity of the indexes of vehicles, y(n, t) = y(n+ N, t). …

Based on variation in nucleotide sequence within restricted regions in the putative C (core)
gene of hepatitis C virus (HCV), four groups of HCV have been postulated in a panel of 44 …

… 1389 [13] Yukawa S, Kikuchi M, Nakayama A, Nishinari K, Sugiyama Y and Tadaki S
2003 Traffic and Granular Flow ’01 ed M Fukui, Y Sugiyama, M Schreckenberg and DE Wolf (…

As an increasing number of field studies of chimpanzees (Pan troglodytes) have achieved
long-term status across Africa, differences in the behavioural repertoires described have …

Lymphocyte recruitment and activation have been implicated in the progression of cerebral
ischemia-reperfusion (I/R) injury, but the roles of specific lymphocyte subpopulations and …

Polymeric micelles incorporating cisplatin (CDDP) were prepared through the polymer-metal
complex formation between CDDP and poly(ethylene glycol)-poly(glutamic acid) block …