Brain histamine H3 receptors are predominantly presynaptic and serve an important
autoregulatory function for the release of histamine and other neurotransmitters. They have …

Histamine regulates neurotransmitter release in the central and peripheral nervous systems
through H3 presynaptic receptors. The existence of the histamine H3 receptor was …

The existence of mouse H3‐receptor isoforms was investigated by PCR analysis and cDNA
cloning. Splicing mechanisms previously reported in various species are conserved in the …

The recent cloning and characterization of the human histamine H3 receptor cDNA marked
a significant step toward a greater understanding of the role of this receptor in the central …

Besides acting in the immune system, histamine is also a neurotransmitter in the central
nervous system. The H 1 R causes central side effects, eg of first generation antihistamines …

From pharmacological studies using histamine antagonists and agonists, it has been
demonstrated that histamine modulates many physiological functions of the hypothalamus …

The histamine H3 receptor was first postulated as a novel class of histamine receptor by the
research group of JC Schwartz'in 1983. Using rat brain tissue, this group went on to define a …

The functional expression of H 4 receptors (H 4 R) within neurons of the central nervous
system has been recently reported, but their role is poorly understood. The present study …

We described previously the cDNA cloning of three functional rat histamine H3 receptor
(rH3R) isoforms as well as the differential brain expression patterns of their corresponding …

Human, guinea pig and rat histamine H3 receptors have been investigated at both
pharmacological and molecular levels in recent years. Here we report the cloning …