Data Supplement
- Supplemental Figures -
Supplemental Figure 1 - AUC sedimentation coefficient distribution of st.mt-CtBP2 (27.2 μM) in its native form and in the presence of 10 μM NAD(H).
Supplemental Figure 2 - AUC sedimentation coefficient distribution of 27.2 μM of st. wt-CtBP2 in its native form and in the presence of 10 μM NAD(H) and varying doses of 4-Cl-HIPP.
Supplemental Figure 3 - Densitometry calculation for GST-wt-CtPB2 and His-wt-CtBP2 and His-G189A-CtBP2.
Supplemental Figure 4 - GST pulldown assay to describe the interaction inhibition between bead immobilized GST-CtBP2 (31-364) and st. wt-CtBP2 in the presence of 10 μM NAD(H) and increasing concentration of either 4-Cl-HIPP or 4-OMe-HIPP (negative control).
Supplemental Figure 5 - Cartoon representing cross-linking reaction.
Supplemental Figure 6 - Blots representing transfection efficiency of cells transfected with either EV, wt or mt-CtBP2 for QPCR assay.
Supplemental Figure 7 - Blots representing transfection efficiency of cells transfected with either EV, wt or mt-CtBP2 for migration assay.