3 July 2008

Dana Schiefelbein, Oliver Seitz, Itamar Goren, Jan Philipp DiBmann, Helmut Schmidt, Malte Bachmann, Robert Sader, Gerd Geisslinger, Josef Pfeilschifter, and Stefan Frank

Keratinocyte-derived VEGF biosynthesis represents a pleiotropic side effect of PPAR agonist troglitazone but not rosiglitazone and involves activation of p38 MAPK: implications for diabetes-impaired skin repair
Published July 3, 2008; doi: 10.1124/mol.108.049395 [Abstract] [PDF] [Data Supplement]  

Jianliang Zhang, Fenqin Xue, and Yongchang Chang

Structural determinants for antagonist pharmacology that distinguishes the 1 GABA_C receptor from GABA_A receptors
Published July 3, 2008; doi: 10.1124/mol.108.048710 [Abstract] [PDF]  

Masahiko Watabe and Toshio Nakaki

Mitochondrial complex I inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells
Published July 3, 2008; doi: 10.1124/mol.108.048546 [Abstract] [PDF]  

1 July 2008

Naeem R Khawaja, Manon Carre, Herve Kovacic, Marie-Anne Esteve, and Diane Braguer

Patupilone-induced apoptosis is mediated by mitochondrial reactive oxygen species through Bim relocalization to mitochondria
Published July 1, 2008; doi: 10.1124/mol.108.048405 [Abstract] [PDF]  

Tao Qi, George Christopoulos, Richard J Bailey, Arthur Christopoulos, Patrick M. Sexton, and Debbie L Hay

Identification of N-terminal receptor activity-modifying protein residues important for CGRP, adrenomedullin and amylin receptor function
Published July 1, 2008; doi: 10.1124/mol.108.047142 [Abstract] [PDF] [Data Supplement]  

26 June 2008

Terry P Kenakin

Seven Transmembrane Receptors as Nature's Prototype Allosteric Protein:De-emphasizing the Geography of Binding (Relates to article by Redka, et al., Fast Forward 13 Jun 08)
Published June 26, 2008; doi: 10.1124/mol.108.050062 [Abstract] [PDF]  

Xiomara A Perez, Tanuja Bordia, J. Michael McIntosh, Sharon R. Grady, and Maryka Quik

Chronic nicotine treatment differentially regulates striatal 642* and 6(non4)2* nAChR expression and function
Published June 26, 2008; doi: 10.1124/mol.108.048843 [Abstract] [PDF]  

Dharini van der Hoeven, Tina C. Wan, and John A. Auchampach

Activation of the A₃ Adenosine Receptor Suppresses Superoxide Production and Chemotaxis of Mouse Bone Marrow Neutrophils
Published June 26, 2008; doi: 10.1124/mol.108.048066 [Abstract] [PDF]  

Frederick S. Jones, Jie Jing, Anthony H. Stonehouse, Anthony Stevens, and Gerald M. Edelman

Caffeine stimulates cytochrome oxidase expression and activity in the striatum in a sexually-dimorphic manner
Published June 26, 2008; doi: 10.1124/mol.108.046888 [Abstract] [PDF]  

Patrice M. Mich and William A. Horne

Alternative Splicing of the Ca²⁺ Channel 4 Subunit Confers Gabapentin Specificity for Inhibition of Ca_v2.1 Trafficking
Published June 26, 2008; doi: 10.1124/mol.108.045153 [Abstract] [PDF]  

25 June 2008

Sean Ekins, Vladyslav Kholodovych, Ni Ai, Michael Sinz, Joseph Gal, Lajos Gera, William J Welsh, Kenneth Bachmann, and Sridhar Mani

COMPUTATIONAL DISCOVERY OF NOVEL LOW MICROMOLAR HUMAN PREGNANE X RECEPTOR ANTAGONISTS
Published June 25, 2008; doi: 10.1124/mol.108.049437 [Abstract] [PDF] [Data Supplement]  

24 June 2008

David Marsolais, Bumsuk Hahm, Kurt H Edelmann, Kevin B Walsh, Miguel Guerrero, Yosuko Hatta, Yoshihiro Kawaoka, Edward Roberts, Michael B Oldstone, and Hugh Rosen

Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza
Published June 24, 2008; doi: 10.1124/mol.108.048769 [Abstract] [PDF] [Data Supplement]  

Federica Fala, William L. Blalock, PierLuigi Tazzari, Alessandra Cappellini, Francesca Chiarini, Giovanni Martinelli, Agostino Tafuri, James A. McCubrey, Lucio Cocco, and Alberto M Martelli

Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor, A443654, in T-Acute Lymphoblastic Leukemia
Published June 24, 2008; doi: 10.1124/mol.108.047639 [Abstract] [PDF]  

Andrea L Kasinski, Yuhong Du, Shala L Thomas, Jing Zhao, Shi-Yong Sun, Fadlo R Khuri, Cun-Yu Wang, Mamoru Shoji, Aiming Sun, James P Snyder, Dennis Liotta, and Haian Fu

Inhibition of IKK-NF-B signaling pathway by EF24, a novel monoketone analogue of curcumin
Published June 24, 2008; doi: 10.1124/mol.108.046201 [Abstract] [PDF] [Data Supplement]  

Yi-Lin Chen, Min-Hui Jian, Chai-Ching Lin, Jung-Cheng Kang, Shee-Ping Chen, Po-Cheng Lin, Putzer-Joseph Hung, Jen-Ren Chen, Wen-Liang Chang, Shinn-Zong Lin, and Horng-Jyh Harn

The induction of orphan nuclear receptor Nur77 expression by n-butylenephthalide as pharmaceuticals on hepatocellular carcinoma (HCC) cells therapy
Published June 24, 2008; doi: 10.1124/mol.107.044800 [Abstract] [PDF]  

23 June 2008

Lisa Mathiasen, Daniel M. Dupont, Anni Christensen, Grant E. Blouse, Jan K. Jensen, Ann Gils, Paul J. Declerck, Troels Wind, and Peter A. Andreasen

A Peptide Accelerating the Conversion of Plasminogen Activator Inhibitor-1 to an Inactive Latent State
Published June 23, 2008; doi: 10.1124/mol.108.046417 [Abstract] [PDF]  

13 June 2008

Sailesh Surapureddi, Ritu Rana, Janardan K Reddy, and Joyce A Goldstein

THE COACTIVATOR NCOA6 MEDIATES THE SYNERGISTIC ACTIVATION OF HUMAN CYTOCHROME P-450 2C9 BY THE CONSTITUTIVE ANDROSTANE RECEPTOR AND HEPATIC NUCLEAR FACTOR-4
Published June 13, 2008; doi: 10.1124/mol.108.048983 [Abstract] [PDF]  

Dar'ya S. Redka, Luca F. Pisterzi, and James W. Wells

Binding of Orthosteric Ligands to the Allosteric Site of the M₂ Muscarinic Cholinergic Receptor
Published June 13, 2008; doi: 10.1124/mol.108.048074 [Abstract] [PDF]  

Jianxi Liu, Thirumalini Vaithianathan, Kandiah Manivannan, Abby Parrill, and Alex M Dopico

Ethanol modulates BK_Ca channels by acting as an adjuvant of calcium
Published June 13, 2008; doi: 10.1124/mol.108.048694 [Abstract] [PDF] [Data Supplement]  

12 June 2008

Yun Ge, Jung S. Byun, Paola De Luca, Geraldine Gueron, Quentin Q Li, Idalia M. Yabe, Sara G. Sadiq-Ali, William D Figg, Jesse Quintero, Cynthia M Haggerty, Adriana De Siervi, and Kevin Gardner

Combinatorial anti-leukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide CPS49 and flavopiridol
Published June 12, 2008; doi: 10.1124/mol.107.040808 [Abstract] [PDF]  

Isamu Aiba, Anwar Hossain, and Macus Tien Kuo

Elevated GSH level increases cadmium resistance through downregulation of Sp1-dependent expression of cadmium transporter ZIP8
Published June 12, 2008; doi: 10.1124/mol.108.046862 [Abstract] [PDF]  

10 June 2008

Gustav Akk, Ping Li, John Bracamontes, David E Reichert, Douglas F Covey, and Joseph H. Steinbach

Mutations of the GABA-A receptor 1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids
Published June 10, 2008; doi: 10.1124/mol.108.048520 [Abstract] [PDF]  

Aditi P Martin, Anna Miller, Luni Emdad, Mohammed Rahmani, Teneille Walker, Clint Mitchell, Michael P Hagan, Margaret A Park, Adly Yacoub, Paul B Fisher, Steven Grant, and Paul Dent

Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression, decreased BAK activation, and not by ERBB receptor mutation
Published June 10, 2008; doi: 10.1124/mol.108.047365 [Abstract] [PDF] [Data Supplement]  

6 June 2008

Rosalind Mann, Mark J. Wigglesworth, and Dan Donnelly

LIGAND-RECEPTOR INTERACTIONS AT THE PARATHYROID HORMONE (PTH) RECEPTORS: SUBTYPE BINDING SELECTIVITY IS MEDIATED VIA AN INTERACTION BETWEEN RESIDUE 23 ON THE LIGAND AND RESIDUE 41 ON THE RECEPTOR
Published June 6, 2008; doi: 10.1124/mol.108.048017 [Abstract] [PDF]  

5 June 2008

Sheryl A Flanagan, Christina M Krokosky, Sudha Mannava, Mikhail A Nikiforov, and Donna S Shewach

MLH1 Deficiency Enhances Radiosensitization with 5-Fluorodeoxyuridine by Increasing DNA Mismatches
Published June 5, 2008; doi: 10.1124/mol.107.043349 [Abstract] [PDF]  

4 June 2008

Vsevolod V Gurevich and Eugenia V Gurevich

Rich tapestry of GPCR signaling and regulatory mechanisms
Published June 4, 2008; doi: 10.1124/mol.108.049015 [Abstract] [PDF]  

Lawrence S. Barak, Ali Salahpour, Xiaodong Zhang, Bernard Masri, Tatyana D. Sotnikova, Amy J. Ramsey, Jonathan D. Violin, Robert J. Lefkowitz, Marc G. Caron, and Raul R. Gainetdinov

Pharmacological Characterization of Membrane-Expressed Human Trace Amine Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer (BRET) cAMP Biosensor
Published June 4, 2008; doi: 10.1124/mol.108.048884 [Abstract] [PDF]  

Pierre-Alexandre Vidi, Benjamin R. Chemel, Chang-Deng Hu, and Val J. Watts

Ligand-Dependant Oligomerization of Dopamine D₂ and Adenosine A_2A Receptors in Living Neuronal Cells
Published June 4, 2008; doi: 10.1124/mol.108.047472 [Abstract] [PDF] [Data Supplement]  

Rama Panford-Walsh, Wibke Singer, Lukas Ruttiger, Saida Hadjab, Justin Tan, Hyun-Soon Geisler, Ulrike Zimmermann, Iris Kopschall, Karin Rohbock, Anna Vieljans, Elmar Oestreicher, and Marlies Knipper

Midazolam Reverses Salicylate Induced Changes in BDNF and Arg3.1 Expression: Implications for Tinnitus Perception and Auditory Plasticity
Published June 4, 2008; doi: 10.1124/mol.108.046375 [Abstract] [PDF]  

Rongbao Zhao, Andong Qiu, Eugenia Tsai, Michaela Jansen, Myles H. Akabas, and I. David Goldman

The Proton-Coupled Folate Transporter (PCFT): Impact on Pemetrexed Transport and on Antifolates Activities as Compared to the Reduced Folate Carrier
Published June 4, 2008; doi: 10.1124/mol.108.045443 [Abstract] [PDF]  

Yi-He Ling, Ruoping Lin, and Roman Perez-Soler

Erlotinib Induces Mitochondrial-Mediated Apoptosis in Human H3255 Non-Small Cell Lung Cancer Cells with EGFR^L858R Mutation through Mitochondrial Oxidative Phosphorylation-Dependent Activation of Bax and Bak
Published June 4, 2008; doi: 10.1124/mol.107.044396 [Abstract] [PDF] [Data Supplement]  

3 June 2008

Helen H. W. Chen, Im-sook Song, Anwar Hossain, Min-Koo Choi, Yoshiaki Yamane, Zheng D. Liang, Jia Lu, Lily Y Wu, Zahid Siddik, leo W. J. Klomp, Naramol Savaraj, and Macus T. Kuo

Elevated Glutathione Levels Confers Cellular Sensitization to Cisplatin Toxicity by Upregulation of Copper Transporter hCtr1
Published June 3, 2008; doi: 10.1124/mol.108.047969 [Abstract] [PDF]  

Ohad Mazor, Ofer Cohen, Chanoch Kronman, Lily Raveh, Dana Stein, Arie Ordentlich, and Avigdor Shafferman

Aging-Resistant Organophosphate Bioscavenger Based on PEGylated Phe338Ala Human Acetylcholinesterase
Published June 3, 2008; doi: 10.1124/mol.108.047449 [Abstract] [PDF]  

Julius Militante, Bei-Wen Ma, Gustav Akk, and Joseph H. Steinbach

Activation and block of the adult muscle-type nicotinic receptor by physostigmine: single-channel studies
Published June 3, 2008; doi: 10.1124/mol.108.047134 [Abstract] [PDF]  

Louis-Philippe Bernier, Ariel R. Ase, Xinkang Tong, Edith Hamel, Dominique Blais, Qi Zhao, Diomedes Logothetis, and Philippe Seguela

Direct modulation of P2X₁ receptor-channels by the lipid phosphatidylinositol 4,5-bisphosphate
Published June 3, 2008; doi: 10.1124/mol.108.047019 [Abstract] [PDF]  

Isabelle Bar, Pieter-Jan Guns, Jessica Metallo, Dorothee Cammarata, Francoise Wilkin, Jean-Marie Boeynaems, Hidde Bult, and Bernard Robaye

Knock-out mice reveal a role for P2Y₆ receptor in macrophages, endothelial cells and vascular smooth muscle cells
Published June 3, 2008; doi: 10.1124/mol.108.046904 [Abstract] [PDF]  

Michael H. Court, Suwagmani Hazarika, Soundararajan Krishnaswamy, Moshe Finel, and J. Andrew Williams

Novel polymorphic human UDP-glucuronosyltransferase (UGT) 2A3: Cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction
Published June 3, 2008; doi: 10.1124/mol.108.045500 [Abstract] [PDF]  

Laura Stanasila, Liliane Abuin, Julien Dey, and Susanna Cotecchia

DIFFERENT INTERNALIZATION PROPERTIES OF THE 1a AND 1b-ADRENERGIC RECEPTOR SUBYTPES: THE POTENTIAL ROLE OF RECEPTOR INTERACTION WITH ARRESTINS AND AP50
Published June 3, 2008; doi: 10.1124/mol.107.043422 [Abstract] [PDF] [Data Supplement]  

Stewart M Knoepp, Manpreet S Chahal, Yuhuan Xie, Zhihong Zhang, Daniel J Brauner, Mark A Hallman, Stephanie A Robinson, Shujie Han, Masaki Imai, Stephen Tomlinson, and Kathryn E Meier

Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells
Published June 3, 2008; doi: 10.1124/mol.107.040105 [Abstract] [PDF]  

29 May 2008

Adebowale Adebiyi, Elizabeth M McNally, and Jonathan H Jaggar

Sulfonylurea Receptor-Dependent and -Independent Pathways Mediate Vasodilation Induced by K_ATP Channel Openers
Published May 29, 2008; doi: 10.1124/mol.108.048165 [Abstract] [PDF]  

Gregg D Stanwood

Protein-Protein Interactions and Dopamine D2 Receptor Signaling: a Calcium Connection (Relates to article by Liu, et al., FastForward 29 April 2008)
Published May 29, 2008; doi: 10.1124/mol.108.049098 [Abstract] [PDF]  

28 May 2008

Marina Galvez-Peralta, Nga T Dai, Dave A Loegering, Karen Flatten, Stephanie Safgren, Jill Wagner, Matthew M Ames, Larry M Karnitz, and Scott H Kaufmann

Overcoming S-Phase Checkpoint-Mediated Resistance: Sequence-Dependent Synergy of Gemcitabine and SN-38 In Human Carcinoma Cell Lines*
Published May 28, 2008; doi: 10.1124/mol.108.047787 [Abstract] [PDF] [Data Supplement]  

Christophe D Proulx, Brian J Holleran, Antony A Boucard, Emanuel Escher, Gaetan Guillemette, and Richard Leduc

Mutational analysis of the conserved Asp^2.50 and ERY motif reveals signaling bias of the urotensin II receptor
Published May 28, 2008; doi: 10.1124/mol.108.045054 [Abstract] [PDF]  

Huixia Zhang, Xiaohui Wu, Honggang Wang, Andrei M. Mikheev, Qingcheng Mao, and Jashvant D. Unadkat

Effect of pregnancy on cytochrome P450 3a and P-glycoprotein expression and activity in the mouse: mechanisms, tissue specificity, and time course
Published May 28, 2008; doi: 10.1124/mol.107.043851 [Abstract] [PDF]  

20 May 2008

Linhao Li, Tao Chen, Joseph Stanton, Tatsuya Sueyoshi, Masahiko Negishi, and Hongbing Wang

The Peripheral Benzodiazepine Receptor Ligand PK11195 is a Novel Antagonist of Human Constitutive Androstane Receptor
Published May 20, 2008; doi: 10.1124/mol.108.046656 [Abstract] [PDF]  

Raymond Evers and Xiaoyan Chu

Perspective: Role of the Murine Organic-Anion Transporting Polypeptide 1b2 (Oatp1b2) in Drug Disposition and Hepatoxicity (Relates to article by Zaher et al., FastForward 15 April 08)
Published May 20, 2008; doi: 10.1124/mol.108.048991 [Abstract] [PDF]  

Li-Chen Ma, Ching-Chuan Kuo, Jin-Fen Liu, Li-Tzong Chen, and Jang-Yang Chang

TRANSCRIPTIONAL REPRESSION OF O⁶-METHYLGUANINE DNA METHYLTRANSFERASE GENE RENDERING CELLS HYPERSENSITIVE TO N,N^'-BIS(2-CHLOROETHYL)-N-NITROSUREA IN CAMPTOTHECIN-RESISTANT CELLS
Published May 20, 2008; doi: 10.1124/mol.107.043620 [Abstract] [PDF] [Data Supplement]  

15 May 2008

Im-Sook Song, Helen H. W. Chen, Isamu Aiba, Anwar Hossain, Zheng D. Liang, Leo Klomp, and Macus Tien Kuo

Transcription Factor Sp1 Plays an Important Role in the Regulation of Copper Homeostasis in Mammalian Cells
Published May 15, 2008; doi: 10.1124/mol.108.046771 [Abstract] [PDF]  

Marie L. Blanke and Antonius M.J. VanDongen

The NR1 M3 domain mediates allosteric coupling in the NMDA receptor
Published May 15, 2008; doi: 10.1124/mol.107.044115 [Abstract] [PDF]  

13 May 2008

Ram N. Trivedi, Xiao-hong Wang, Elena Jelezcova, Eva M. Goellner, Jiangbo Tang, and Robert W. Sobol

Human methyl purine DNA glycosylase and DNA polymerase expression collectively predict sensitivity to temozolomide
Published May 13, 2008; doi: 10.1124/mol.108.045112 [Abstract] [PDF]  

Jun-ichi Koizumi, Takashi Kojima, Noriko Ogasawara, Ryuta Kamekura, Makoto Kurose, Mitsuru Go, Atsushi Harimaya, Masaki Murata, Makoto Osanai, Hideki Chiba, Tetsuo Himi, and Norimasa Sawada

PKC enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation
Published May 13, 2008; doi: 10.1124/mol.107.043711 [Abstract] [PDF] [Data Supplement]  

12 May 2008

Katrien Francois, Joeri Auwerx, Dominique Schols, and Jan Balzarini

SIMIAN IMMUNODEFICIENCY VIRUS (SIV) IS SUSCEPTIBLE TO INHIBITION BY CARBOHYDRATE-BINDING AGENTS (CBAS) IN A SIMILAR MANNER AS HUMAN IMMUNODEFICIENCY VIRUS (HIV). IMPLICATIONS FOR FURTHER PRECLINICAL DRUG DEVELOPMENT
Published May 12, 2008; doi: 10.1124/mol.108.047621 [Abstract] [PDF]  

9 May 2008

Mieke Gouwy, Sofie Struyf, Samuel Noppen, Evemie Schutyser, Jean-Yves Springael, Marc Parmentier, Paul Proost, and Jo Van Damme

Synergy between co-produced CC and CXC chemokines in monocyte chemotaxis through receptor mediated events
Published May 9, 2008; doi: 10.1124/mol.108.045146 [Abstract] [PDF]  

Alexander Stepanov, Karin C Nitiss, Geoffrey Neale, and John L. Nitiss

Enhancing drug accumulation in S. cerevisiae by repression of pleiotropic drug resistance genes with chimeric transcription repressors
Published May 9, 2008; doi: 10.1124/mol.107.044651 [Abstract] [PDF]  

8 May 2008

Maoqing Dong, Polo C.-H. Lam, Delia I. Pinon, Patrick M. Sexton, Ruben Abagyan, and Laurence J. Miller

Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding
Published May 8, 2008; doi: 10.1124/mol.108.047209 [Abstract] [PDF]  

Eric S Muise, Barbara azzolina, David W Kuo, Mohamed El-Sherbeini, Yejun Tan, Xiling Yuan, James Mu, John R Thompson, Joel P Berger, and Kenny K. Wong

Adipose Fibroblast Growth Factor 21 is Up-Regulated by PPAR and Altered Metabolic states
Published May 8, 2008; doi: 10.1124/mol.108.044826 [Abstract] [PDF]  

7 May 2008

Christine Borner, Juergen Kraus, Andrea Bedini, Burkhart Schraven, and Volker Hollt

T cell receptor/CD28-mediated activation of human T lymphocytes induces expression of functional µ-opioid receptors
Published May 7, 2008; doi: 10.1124/mol.108.046029 [Abstract] [PDF]  

Chiara Riganti, Sophie Doublier, Costanzo Costamagna, Elisabetta Aldieri, Gianpiero Pescarmona, Dario Ghigo, and Amalia Bosia

Activation of NF-kB pathway by simvastatin and RhoA silencing increases doxorubicin cytotoxicity in human colon cancer HT29 cells
Published May 7, 2008; doi: 10.1124/mol.108.045286 [Abstract] [PDF] [Data Supplement]  

6 May 2008

Igor A Schepetkin, Liliya N Kirpotina, Jun Tian, Andrei I Khlebnikov, Richard D. Ye, and Mark T Quinn

Identification of Novel Formyl Peptide Receptor-Like 1 Agonists that Induce Macrophage Tumor Necrosis Factor Production
Published May 6, 2008; doi: 10.1124/mol.108.046946 [Abstract] [PDF] [Data Supplement]  

Kuicheon Choi, Elahe Mollapour, Jae H Choi, and Stephen B Shears

Cellular energetic status supervises the synthesis of bis-diphosphoinositol tetrakisphosphate ("InsP8"), independently of AMP-activated protein kinase
Published May 6, 2008; doi: 10.1124/mol.107.044628 [Abstract] [PDF]  

5 May 2008

Tse-Yu Wu, Caleb M. Smith, Steven M. Sine, and Mark M. Levandoski

Morantel Allosterically Enhances Channel Gating of Neuronal Nicotinic Acetylcholine 32 Receptors
Published May 5, 2008; doi: 10.1124/mol.107.044388 [Abstract] [PDF]  

2 May 2008

jean-charles hoda, Wenli Gu, Marc Friedli, Hilary Phillips, Sonia Bertrand, Srylianos E. Antonarakis, David Goudie, Richard Roberts, Ingrid Scheffer, Carla Marini, Jayesh Patel, Samuel F. Berkovic, John C. Mulley, Ortrud K. Steinlein, and Daniel C. Bertrand

Human nocturnal frontal lobe epilepsy: pharmocogenomic profiles of pathogenic nAChR -subunit mutations outside the ion channel pore
Published May 2, 2008; doi: 10.1124/mol.107.044545 [Abstract] [PDF]  

29 April 2008

Yong Liu, David C Buck, and Kim A Neve

Novel Interaction of the Dopamine D₂ Receptor and the Ca²⁺-Binding Protein S100B: Role in D₂ Receptor Function
Published April 29, 2008; doi: 10.1124/mol.108.044925 [Abstract] [PDF]  

Eunice Y Yuen, Yi Ren, and Zhen Yan

PSD-95 and Calcineurin Control the Sensitivity of NMDA Receptors to Calpain Cleavage in Cortical Neurons
Published April 29, 2008; doi: 10.1124/mol.108.046813 [Abstract] [PDF]  

Jane A Dickinson, James N. C. Kew, and Susan Wonnacott

Presynaptic 7 and 2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms
Published April 29, 2008; doi: 10.1124/mol.108.046623 [Abstract] [PDF]  

15 April 2008

Hani Zaher, Henriette E Meyer zu Schwabedissen, Rommel G Tirona, Melissa L Cox, Leslie A Obert, Nidhi Agrawal, Joe Palandra, Jeffrey L Stock, Richard B. Kim, and Joseph A Ware

Targeted Disruption of Murine Organic Anion-Transporting Polypeptide 1b2 (oatp1b2/Slco1b2) Significantly Alters Disposition of Prototypical Drug Substrates Pravastatin and Rifampin
Published April 15, 2008; doi: 10.1124/mol.108.046458 [Abstract] [PDF]  

3 April 2008

Jiansong Luo, John M. Busillo, and Jeffrey L. Benovic

M₃ Muscarinic Acetylcholine Receptor-Mediated Signaling is Regulated by Distinct Mechanisms
Published April 3, 2008; doi: 10.1124/mol.107.044750 [Abstract] [PDF]  

29 May 2007

Pia C Jensen, Rie Nygaard, Stefanie Thiele, Amy Elder, Guoming Zhu, Roland Kolbeck, Shomir Ghosh, Thue W Schwartz, and Mette M Rosenkilde

MOLECULAR INTERACTION OF A POTENT NON-PEPTIDE AGONIST WITH THE CHEMOKINE RECEPTOR CCR8
Published May 29, 2007; doi: 10.1124/mol.107.035543 [Abstract] [PDF]  

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