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Molecular Pharmacology

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Molecular Pharmacology is excited to WELCOME six new Editorial Advisory Board members.

Call for Papers - Special Section on Sphingolipids for March 2024

  • Wallace Chan
  • Upacicalcet Binds to the Amino Acid Binding Site of CaSR
  • Extrachromosomal circular DNAs and CRISPR-Cas9 System
  • α-Conotoxin Binding Site on the GABAB Receptor
  • Upacicalcet Binds to the Amino Acid Binding Site of CaSR
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Latest Fast Forward Articles

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    Hexahydroquinoline Derivatives are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56
    Alexander L Vizurraga, Michael J Robertson, Maiya Yu, Georgios Skiniotis and Gregory G Tall
    Molecular Pharmacology June 8, 2023, MOLPHARM-AR-2023-000688; DOI: https://doi.org/10.1124/molpharm.123.000688
  • You have access
    Modulation of Kv7 Channel Currents by Echinocystic Acid
    DanDan Geng, Yaning Li, Rong Zheng, Runmeng Wang, Bo Yang, Huaxing Zhang, Yang Zhang and Fan Zhang
    Molecular Pharmacology June 6, 2023, MOLPHARM-AR-2022-000640; DOI: https://doi.org/10.1124/molpharm.122.000640
  • You have access
    The potential antidepressant compound Org 34167 modulates HCN channels via a novel mode of action
    Chaseley E McKenzie, Andrew Hung, A Marie Phillips, Ming S Soh, Christopher A. Reid and Ian C Forster
    Molecular Pharmacology June 6, 2023, MOLPHARM-AR-2023-000676; DOI: https://doi.org/10.1124/molpharm.123.000676
  • You have access
    A Point Mutation at C151 of Keap1 of Mice Abrogates NRF2 Signaling, Cytoprotection In Vitro and Hepatoprotection In Vivo by Bardoxolone Methyl (CDDO-Me)
    Tonibelle Gatbonton-Schwager, Yoko Yagishita, Tanvi Joshi, Nobunao Wakabayashi, Harini Srinivasan, Takafumi Suzuki, Masayuki Yamamoto and Thomas W Kensler
    Molecular Pharmacology May 15, 2023, MOLPHARM-AR-2023-000671; DOI: https://doi.org/10.1124/molpharm.123.000671
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    Multi-omics analyses identify PREPL as a key regulator of protein trafficking, a pathway underlying Alzheimer's disease pathogenesis
    Mariana Lemos Duarte, Minghui Wang, Ivone Gomes, Chenge Liu, Ali Sharma, Amanda K Fakira, Achla Gupta, Seshat M. Mack, Bin Zhang and Lakshmi A. Devi
    Molecular Pharmacology May 5, 2023, MOLPHARM-AR-2022-000641; DOI: https://doi.org/10.1124/molpharm.122.000641
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    Differential Activity of Orthosteric Agonists and Allosteric Modulators at Metabotropic Glutamate Receptor 7
    Xia Lei, Christopher Hofmann, Alice L Rodriguez and Colleen Niswender
    Molecular Pharmacology April 27, 2023, MOLPHARM-AR-2023-000678; DOI: https://doi.org/10.1124/molpharm.123.000678
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About Molecular Pharmacology

Molecular Pharmacology publishes findings derived from the application of innovative structural biology, biochemistry, biophysics, physiology, genetics, and molecular biology to basic pharmacological problems that provide mechanistic insights that are broadly important for the fields of pharmacology and toxicology. Relevant topics include:

  • Molecular Signaling / Mechanism of Drug Action
  • Chemical Biology / Drug Discovery
  • Structure of Drug-Receptor Complex
  • Systems Analysis of Drug Action
  • Drug Transport / Metabolism

Current issue

Molecular Pharmacology: 103 (6)
Molecular Pharmacology
Vol. 103, Issue 6
1 Jun 2023
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)

Molecular Pharmacology is published continuously. New articles are added as they become ready and assigned to monthly issues. Check this site for new content or sign up for content alerts.

EDITOR'S CHOICE ARTICLES FOR JUNE 2023:

  • In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A2A Receptor Antagonist/Inverse Agonist
  • Determinants of Subtype-Selectivity of the Anthelmintic Paraherquamide A on Caenorhabditis elegans Nicotinic Acetylcholine Receptors - open access
  • Most Cited
  • Most Read
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
More...
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