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Molecular Pharmacology

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Table of Contents

September 01, 2021; Volume 100,Issue 3

Articles

  • You have access
    Thermal Proteome Profiling Reveals Glutathione Peroxidase 4 as the Target of the Autophagy Inducer Conophylline
    Junya Kakegawa, Satoshi Ohtsuka, Masahiro Yokoyama, Toru Hosoi, Koichiro Ozawa and Takashi Hatanaka
    Molecular Pharmacology September 2021, 100 (3) 181-192; DOI: https://doi.org/10.1124/molpharm.121.000243
  • You have access
    Selection and Characterization of FD164, a High-Affinity Signal Regulatory Protein α Variant with Balanced Safety and Effectiveness, from a Targeted Epitope Mammalian Cell-Displayed Antibody Library
    Zhihong Wang, Naijing Hu, Xinying Li, Haitao Wang, Caiping Ren, Chunxia Qiao, Guojiang Chen, Jing Wang, Liuzhong Zhou, Jiaguo Wu, Dingmu Zhang, Jiannan Feng, Beifen Shen, Hui Peng and Longlong Luo
    Molecular Pharmacology September 2021, 100 (3) 193-202; DOI: https://doi.org/10.1124/molpharm.120.000202
  • Open Access
    Physiological Temperature Changes Fine-Tune β2- Adrenergic Receptor-Induced Cytosolic cAMP Accumulation
    Dennis Faro, Ingrid Boekhoff, Thomas Gudermann and Andreas Breit
    Molecular Pharmacology September 2021, 100 (3) 203-216; DOI: https://doi.org/10.1124/molpharm.121.000309
  • You have access
    Mice Expressing Regulators of G protein Signaling–insensitive Gαo Define Roles of μ Opioid Receptor Gαo and Gαi Subunit Coupling in Inhibition of Presynaptic GABA Release
    Courtney A. Bouchet, Kylie B. McPherson, Ming-hua Li, John R. Traynor and Susan L. Ingram
    Molecular Pharmacology September 2021, 100 (3) 217-223; DOI: https://doi.org/10.1124/molpharm.121.000249
  • You have access
    Differential Reversible and Irreversible Interactions between Benzbromarone and Human Cytochrome P450s 3A4 and 3A5
    Lloyd Wei Tat Tang, Ravi Kumar Verma, Ren Ping Yong, Xin Li, Lili Wang, Qingsong Lin, Hao Fan and Eric Chun Yong Chan
    Molecular Pharmacology September 2021, 100 (3) 224-236; DOI: https://doi.org/10.1124/molpharm.121.000256
  • You have access
    High-Throughput Screening of TRPV1 Ligands in the Light of the Bioluminescence Resonance Energy Transfer Technique
    Yann Chappe, Pauline Michel, Alexandre Joushomme, Solène Barbeau, Sandra Pierredon, Luc Baron, André Garenne, Florence Poulletier De Gannes, Annabelle Hurtier, Stanislas Mayer, Isabelle Lagroye, Jean-François Quignard, Thomas Ducret, Vincent Compan, Christelle Franchet and Yann Percherancier
    Molecular Pharmacology September 2021, 100 (3) 237-257; DOI: https://doi.org/10.1124/molpharm.121.000271
  • Functional Interaction between Transient Receptor Potential V4 Channel and Neuronal Calcium Sensor 1 and the Effects of Paclitaxel
    Open Access
    Functional Interaction between Transient Receptor Potential V4 Channel and Neuronal Calcium Sensor 1 and the Effects of Paclitaxel
    Julio C. Sánchez and Barbara E. Ehrlich
    Molecular Pharmacology September 2021, 100 (3) 258-270; DOI: https://doi.org/10.1124/molpharm.121.000244
  • Open Access
    Ligand-Independent G Protein–Coupled Estrogen Receptor/G Protein–Coupled Receptor 30 Activity: Lack of Receptor-Dependent Effects of G-1 and 17β-Estradiol
    Julia Tutzauer, Ernesto Gonzalez de Valdivia, Karl Swärd, Ioannis Alexandrakis Eilard, Stefan Broselid, Robin Kahn, Björn Olde and L. M. Fredrik Leeb-Lundberg
    Molecular Pharmacology September 2021, 100 (3) 271-282; DOI: https://doi.org/10.1124/molpharm.121.000259
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    The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3)
    Jérémy Berthelet, Christina Michail, Linh-Chi Bui, Louise Le Coadou, Valentina Sirri, Li Wang, Nicolas Dulphy, Jean-Marie Dupret, Christine Chomienne, Fabien Guidez and Fernando Rodrigues-Lima
    Molecular Pharmacology September 2021, 100 (3) 283-294; DOI: https://doi.org/10.1124/molpharm.121.000303
  • You have access
    Dynamic Expression of Transient Receptor Potential Vanilloid-3 and Integrated Signaling with Growth Factor Pathways during Lung Epithelial Wound Repair following Wood Smoke Particle and Other Forms of Lung Cell Injury
    Katherine L. Burrell, Nam D. Nguyen, Cassandra E. Deering-Rice, Tosifa A. Memon, Marysol Almestica-Roberts, Emmanuel Rapp, Samantha N. Serna, John G. Lamb and Christopher A. Reilly
    Molecular Pharmacology September 2021, 100 (3) 295-307; DOI: https://doi.org/10.1124/molpharm.121.000280

Erratum

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    Correction to “High-Throughput Screening of Transient Receptor Potential Channel 1 Ligands in the Light of the Bioluminescence Resonance Energy Transfer Technique”
    Molecular Pharmacology September 2021, 100 (3) 308; DOI: https://doi.org/10.1124/molpharm.121.000271err
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Molecular Pharmacology: 100 (3)
Molecular Pharmacology
Vol. 100, Issue 3
1 Sep 2021
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  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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