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Molecular Pharmacology

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Table of Contents

April 01, 2022; Volume 101,Issue 4

Axelrod Symposium Protein Kinases in Tune - Special Section

  • Open Access
    G-Protein Coupled Receptor Signaling and Mammalian Target of Rapamycin Complex 1 Regulation
    Chase H. Melick, Tshering D. Lama-Sherpa, Adna Curukovic and Jenna L. Jewell
    Molecular Pharmacology April 2022, 101 (4) 181-190; DOI: https://doi.org/10.1124/molpharm.121.000302
  • Open Access
    Degraders: The Ultimate Weapon Against Amplified Driver Kinases in Cancer
    Pedro Torres-Ayuso and John Brognard
    Molecular Pharmacology April 2022, 101 (4) 191-200; DOI: https://doi.org/10.1124/molpharm.121.000306
  • You have access
    CCT and CCT-Like Modular Protein Interaction Domains in WNK Signaling
    Clinton A. Taylor and Melanie H. Cobb
    Molecular Pharmacology April 2022, 101 (4) 201-212; DOI: https://doi.org/10.1124/molpharm.121.000307
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    mTOR Regulation of AGC Kinases: New Twist to an Old Tail
    Timothy R. Baffi and Alexandra C. Newton
    Molecular Pharmacology April 2022, 101 (4) 213-218; DOI: https://doi.org/10.1124/molpharm.121.000310
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    The Tails of Protein Kinase A
    Susan S. Taylor, Kristoffer Søberg, Evan Kobori, Jian Wu, Sabine Pautz, Friedrich W. Herberg and Bjørn Steen Skålhegg
    Molecular Pharmacology April 2022, 101 (4) 219-225; DOI: https://doi.org/10.1124/molpharm.121.000315

Articles

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    A Recombinant Dimethylarginine Dimethylaminohydrolase-1–Based Biotherapeutics to Pharmacologically Lower Asymmetric Dimethyl Arginine, thus Improving Postischemic Cardiac Function and Cardiomyocyte Mitochondrial Activity
    Young Lee, Jaipal Singh, Susan R. Scott, Bradley Ellis, Pinar Zorlutuna and Meijing Wang
    Molecular Pharmacology April 2022, 101 (4) 226-235; DOI: https://doi.org/10.1124/molpharm.121.000394
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    A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient KV11.1 (hERG) Variants
    Christian L. Egly, Daniel J. Blackwell, Jeffrey Schmeckpeper, Brian P. Delisle, C. David Weaver and Björn C. Knollmann
    Molecular Pharmacology April 2022, 101 (4) 236-245; DOI: https://doi.org/10.1124/molpharm.121.000421
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    Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors
    Jon Merlin, Julia Park, Teresa H. Vandekolk, Stewart A. Fabb, Jeanne Allinne, Roger J. Summers, Christopher J. Langmead and Darren M. Riddy
    Molecular Pharmacology April 2022, 101 (4) 246-256; DOI: https://doi.org/10.1124/molpharm.121.000422
  • Yeast <em>β</em>-glucan Increases Etoposide Sensitivity in Lung Cancer Cell Line A549 by Suppressing Nuclear Factor Erythroid 2-Related Factor 2 via the Noncanonical Nuclear Factor Kappa B Pathway
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    Yeast β-glucan Increases Etoposide Sensitivity in Lung Cancer Cell Line A549 by Suppressing Nuclear Factor Erythroid 2-Related Factor 2 via the Noncanonical Nuclear Factor Kappa B Pathway
    Ferbian Milas Siswanto, Akiyoshi Tamura, Rika Sakuma and Susumu Imaoka
    Molecular Pharmacology April 2022, 101 (4) 257-273; DOI: https://doi.org/10.1124/molpharm.121.000475

Erratum

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    Correction to “Activation of the Orphan G Protein–Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment”
    Molecular Pharmacology April 2022, 101 (4) 274; DOI: https://doi.org/10.1124/mol.116.107714err
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In this issue

Molecular Pharmacology: 101 (4)
Molecular Pharmacology
Vol. 101, Issue 4
1 Apr 2022
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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