Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)

Laboratory of Biomolecular Research, Villigen, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biology, Paul Scherrer Institute, Zürich, Switzerland (F.M.H., A.R., D.M., D.B.V.); Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada (F.M.H., B.P., J.Z., B.B., C.L., M.B.); MRC Laboratory of Molecular Biology, Cambridge, United Kingdom (F.M.H.); The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom (B.P.); Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria (D.M.); Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan (A.I.); Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, United Kingdom (D.B.V.); and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom (D.B.V.)