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Data Supplement
- Supplemental Data -
Supplementary Figure S1: The results of SEC-HPLC of 5 selected antibodies under natural conditions. Except for 1B4, which has the ability to form polymers, most of the other antibodies are in the form of monomers.
Supplementary Figure S2: Fitting graph of association/dissociation of the three candidate antibodies. The KD values of each antibody were listed as showinthegraph.
Supplementary Figure S3: Analysis of blocking activity between candidate antibodies and differentgands of Siglec-15.
Supplementary Figure S4: Evaluation of the biological activity of candidate antibodies invitro.
Supplementary Figure S5: The expression level of EGFR on the cell surface of H157(S15+).
Supplementary Table S1
- Supplemental Data -