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Molecular Pharmacology

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Research ArticleArticle
Open Access

Upacicalcet Is a Novel Secondary Hyperparathyroidism Drug that Targets the Amino Acid Binding Site of Calcium-Sensing Receptor 

Hirofumi Sato, Sei Murakami, Yusuke Horii, Go Nishimura, Ryosuke Iwai, Moritaka Goto and Naoki Takahashi
Molecular Pharmacology October 2022, 102 (4) 183-195; DOI: https://doi.org/10.1124/molpharm.122.000522
Hirofumi Sato
Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., Mie, Japan
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Sei Murakami
Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., Mie, Japan
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Yusuke Horii
Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., Mie, Japan
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Go Nishimura
Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., Mie, Japan
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Ryosuke Iwai
Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., Mie, Japan
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Moritaka Goto
Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., Mie, Japan
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  • ORCID record for Moritaka Goto
Naoki Takahashi
Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., Mie, Japan
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Article Information

vol. 102 no. 4 183-195
DOI 
https://doi.org/10.1124/molpharm.122.000522
PubMed 
36122913

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received February 18, 2022
  • Accepted July 14, 2022
  • Published online September 18, 2022.

Article Versions

  • Earlier version (August 5, 2022 - 08:48).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2022 The Author(s) This is an open access article distributed under the CC BY Attribution 4.0 International license.

Author Information

  1. Hirofumi Sato,
  2. Sei Murakami,
  3. Yusuke Horii,
  4. Go Nishimura,
  5. Ryosuke Iwai,
  6. Moritaka Goto, and
  7. Naoki Takahashi
  1. Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., Mie, Japan
  1. Address correspondence to:
    Moritaka Goto, Pharmaceuticals Research Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd., 363 Shiosaki, Hokusei-cho, Inabe, Mie, 511-0406, Japan. E-mail: mo_gotoh{at}skk-net.com
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Molecular Pharmacology: 102 (4)
Molecular Pharmacology
Vol. 102, Issue 4
1 Oct 2022
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Research ArticleArticle

Upacicalcet Binds to the Amino Acid Binding Site of CaSR

Hirofumi Sato, Sei Murakami, Yusuke Horii, Go Nishimura, Ryosuke Iwai, Moritaka Goto and Naoki Takahashi
Molecular Pharmacology October 1, 2022, 102 (4) 183-195; DOI: https://doi.org/10.1124/molpharm.122.000522

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Research ArticleArticle

Upacicalcet Binds to the Amino Acid Binding Site of CaSR

Hirofumi Sato, Sei Murakami, Yusuke Horii, Go Nishimura, Ryosuke Iwai, Moritaka Goto and Naoki Takahashi
Molecular Pharmacology October 1, 2022, 102 (4) 183-195; DOI: https://doi.org/10.1124/molpharm.122.000522
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