Table of Contents

Articles

• Open Access

  Multiplex G Protein–Coupled Receptor Screen Reveals Reliably Acting Agonists and a Gq-Phospholipase C Coupling Mode of GPR30/GPER1

  Nicole Urban, Marion Leonhardt and Michael Schaefer

  Molecular Pharmacology February 2023, 103 (2) 48-62; DOI: https://doi.org/10.1124/molpharm.122.000580
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  Insights Into the Differential Desensitization of α4β2 Nicotinic Acetylcholine Receptor Isoforms Obtained With Positive Allosteric Modulation of Mutant Receptors

  Roger L. Papke and Clare Stokes

  Molecular Pharmacology February 2023, 103 (2) 63-76; DOI: https://doi.org/10.1124/molpharm.122.000591
• Open Access

  Differences in Sustained Cellular Effects of MET inhibitors Are Driven by Prolonged Target Engagement and Lysosomal Retention

  Nina Berges, Jan Henrik Klug, Anna Eicher, Jennifer Loehr, Daniel Schwarz, Joerg Bomke, Birgitta Leuthner, Dominique Perrin and Oliver Schadt

  Molecular Pharmacology February 2023, 103 (2) 77-88; DOI: https://doi.org/10.1124/molpharm.122.000590
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  Open Access

  The Isoleucine at Position 118 in Transmembrane 2 Is Responsible for the Selectivity of Xamoterol, Nebivolol, and ICI89406 for the Human β1-Adrenoceptor

  Victor Jun Yu Lim, Richard G. W. Proudman, Stefania Monteleone, Peter Kolb and Jillian G. Baker

  Molecular Pharmacology February 2023, 103 (2) 89-99; DOI: https://doi.org/10.1124/molpharm.122.000583
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  A Complete Endocannabinoid Signaling System Modulates Synaptic Transmission between Human Induced Pluripotent Stem Cell–Derived Neurons

  Melissa J. Asher, Hannah M. McMullan, Ao Dong, Yulong Li and Stanley A. Thayer

  Molecular Pharmacology February 2023, 103 (2) 100-112; DOI: https://doi.org/10.1124/molpharm.122.000555