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Differences in Sustained Cellular Effects of MET inhibitors Are Driven by Prolonged Target Engagement and Lysosomal Retention

Nina Berges, Jan Henrik Klug, Anna Eicher, Jennifer Loehr, Daniel Schwarz, Joerg Bomke, Birgitta Leuthner, Dominique Perrin and Oliver Schadt
Molecular Pharmacology February 2023, 103 (2) 77-88; DOI: https://doi.org/10.1124/molpharm.122.000590
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Research ArticleArticle

MET Inhibitors—Mechanisms of Prolonged Target Engagement

Nina Berges, Jan Henrik Klug, Anna Eicher, Jennifer Loehr, Daniel Schwarz, Joerg Bomke, Birgitta Leuthner, Dominique Perrin and Oliver Schadt
Molecular Pharmacology February 1, 2023, 103 (2) 77-88; DOI: https://doi.org/10.1124/molpharm.122.000590
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