SCD1 | [Inhibition] Desaturation of saturated fatty acids—competitive formation of monounsaturated fatty acids | Promote | Luis et al., 2021 |
CD 36 | [Upregulation] Increase in the import of fatty acids into cells | Promote | Pizon et al., 2018 |
Transferin receptor | [Upregulation] Increase in unstable iron pool | Promote | Yang and Stockwell, 2008 |
FABP | [Inhibition] Creation of lipid droplets in cells | promote | |
Heat shock protein β-1 | [Knockdown] Increase in iron uptake | Promote | Sun et al., 2015 |
FANCD2 | [Knockdown] Increase in iron uptake | Promote | Song et al., 2016 |
Ferritin heavy chain 1 | [Knockdown] Reduction in the content of iron-binding proteins in the cell | Promote | Yang and Stockwell, 2008 |
Heme oxygenase | [Upregulation] Enhancement of heme catabolism and iron release | Promote | Kwon et al., 2015 |
SGLT2 | [Inhibition] Increase in AMPK phosphorylation | Promote | Zhou et al., 2020b |
Erastin/sorafenib | [Increase in concentration] Blockage of system xc- | Promote | Lin et al., 2020 |
Iron response element-binding protein 2 | [Knockdown] Regulation of RNA translation responsible for iron consumption | Inhibit | Dixon et al., 2012 |
NCOA4 | [Knockdown] Slowdown in the degradation of ferritin in the process of autophagy | Inhibit | Mancias et al., 2014 |
Ferroportin | [Upregulation] Increase in transport of iron outside the cell | Inhibit | Wang et al., 2018 |
Autophagy-related protein 3 | [Knockdown] Slowdown in the degradation of ferritin in the process of autophagy | Inhibit | Gao et al., 2016 |