Article Figures & Data
Figures
Tables
Data Supplement
- Supplemental Data -
Figure S1: Comparison of Allosteric Sites in Test Set GPCRs between ‘Apo’ and ‘Holo’ States
Figure S2: Protein RMSDs from Production Simulations
Figure S3: Electron Density Profiles from Production Simulations
Figure S4: Orthosteric Site Predictions
Figure S5: Interactions made with Allosteric Modulators from the Test Set
Figure S6: Comparison of Extracellular Vestibule of M2 Muscarinic Receptor
Figure S7: FTMap Results for Test Set GPCRs
Figure S8: Additional Predicted Sites on the Mu Opioid Receptor
Figure S9: Comparison of Putative Allosteric Site across Activation States of the Mu Opioid Receptor (MOR)
Figure S10: Predicted Allosteric Sites on the M2 Muscarinic Receptor (M2)
Table S1: Summary of GPCRs used in the study
Table S2: Information on PDB structures employed
- Supplemental Data -