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BAY58-2667 Activates Different Soluble Guanylyl Cyclase Species by Distinct Mechanisms that Indicate Its Principal Target in Cells is the Heme-Free Soluble Guanylyl Cyclase-Heat Shock Protein 90 Complex

Yue Dai and Dennis J. Stuehr
Molecular Pharmacology May 2023, 103 (5) 286-296; DOI: https://doi.org/10.1124/molpharm.122.000624

Article Information

vol. 103 no. 5 286-296
DOI 
https://doi.org/10.1124/molpharm.122.000624
PubMed 
36868790
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 14, 2022
  • Accepted February 7, 2023
  • Published online April 13, 2023.

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Copyright & Usage 
Copyright © 2023 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yue Dai and
  2. Dennis J. Stuehr
  1. Department of Inflammation and Immunity, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio
  1. Address correspondence to:
    Dennis J. Stuehr, Department of Inflammation and Immunity, NC-22, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195. E-mail: stuehrd{at}ccf.org
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BAY58-2667 Activates sGC Species by Different Mechanisms

Yue Dai and Dennis J. Stuehr
Molecular Pharmacology May 1, 2023, 103 (5) 286-296; DOI: https://doi.org/10.1124/molpharm.122.000624
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