Abstract
Serotonin was identified as the potent (Na+ + K+-ATPase inhibitor previously reported to be present in the coelenterate Palythoa caribaeorum. As the serotonin-creatinine sulfate complex (commercial preparations) its inhibitory potency is sharply reduced. Inhibition is fully restored on fractionation of the complex on cation-exchange resins.
ACKNOWLEDGMENTS We thank Professor J. del Castillo and Mr. F. McKenzie for their generous supply of E. electricus and P. caribaeorum.
- Copyright © 1977 by Academic Press, Inc.
MolPharm articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|
Log in using your username and password
Purchase access
You may purchase access to this article. This will require you to create an account if you don't already have one.