Abstract
Cytochrome P-450 in rat liver nuclear membranes of untreated, PB-pretreated, or 3-MC-pretreated animals was spectrally similar to corresponding liver microsomes. Epoxide hydrase activity of liver nuclear membrane and microsomes was induced by PB administration; 3-MC did not cause any induction. The same results were obtained when either the DNase digestion method or sucrose density centrifugation technique for preparation of nuclear membranes was used.
- Copyright © 1979 by Academic Press, Inc.
In this issue
Rat Hepatic Nuclear Cytochrome P-450 and Epoxide Hydrase in Membranes Prepared by Two Methods: Similarities with the Microsomal Enzymes
