Abstract
Isogabaculine reacts with pyridoxal phosphate to form N-meta-carboxyphenylpyridoxamine phosphate as does its natural isomer gabaculine. The two compounds are almost equipotent in vitro and in vivo in inhibiting 4-amino-butyrate (GABA) aminotransferase and L-ornithine aminotransferase and in elevating brain GABA levels.
- Copyright © 1979 by Academic Press, Inc.
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