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Table of Contents

September 01, 1982; Volume 22,Issue 2

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Enzyme regulatory site-directed drugs. MOdulation of thymidine triphosphate inhibition of thymidine kinase by 5'-amino-5'-deoxythymidine.
P H Fischer and D Baxter

Molecular Pharmacology September 1982, 22 (2) 231-234;
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N-oxidation of phentermine to N-hydroxyphentermine by a reconstituted cytochrome P-450 oxidase system from rabbit liver.
J D Duncan and A K Cho

Molecular Pharmacology September 1982, 22 (2) 235-238;
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Microsomal reduction of gentian violet. Evidence for cytochrome P-450-catalyzed free radical formation.
W G Harrelson and R P Mason

Molecular Pharmacology September 1982, 22 (2) 239-242;
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Characterization of solubilized serotonin (S2) receptors in rat brain.
B Ilien, H Gorissen and P M Laduron

Molecular Pharmacology September 1982, 22 (2) 243-249;
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Heterogeneity of adenosine A1 receptor binding in brain tissue.
K M Murphy and S H Snyder

Molecular Pharmacology September 1982, 22 (2) 250-257;
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Characterization of coexisting alpha 1- and beta 2-adrenergic receptors on a cloned muscle cell line, BC3H-1.
R J Hughes, M R Boyle, R D Brown, P Taylor and P A Insel

Molecular Pharmacology September 1982, 22 (2) 258-266;
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Magnesium regulation of the beta-receptor-adenylate cyclase complex. I. Effects of manganese on receptor binding and cyclase activation.
S Y Cech and M E Maguire

Molecular Pharmacology September 1982, 22 (2) 267-273;
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Magnesium regulation of the beta-receptor-adenylate cyclase complex. II. Sc3+ as a Mg2 antagonist.
M E Maguire

Molecular Pharmacology September 1982, 22 (2) 274-280;
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Further characterization of structural requirements for agonists at the striatal dopamine D-1 receptor. Studies with a series of monohydroxyaminotetralins on dopamine-sensitive adenylate cyclase and a comparison with dopamine receptor binding.
M P Seiler and R Markstein

Molecular Pharmacology September 1982, 22 (2) 281-289;
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Dopamine receptor of the porcine anterior pituitary gland. Evidence for two affinity states discriminated by both agonists and antagonists.
A De Lean, B F Kilpatrick and M G Caron

Molecular Pharmacology September 1982, 22 (2) 290-297;
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Dopamine receptor of the porcine anterior pituitary gland. Effects of N-ethylmaleimide and heat on ligand binding mimic the effects of guanine nucleotides.
B F Kilpatrick, A De Lean and M G Caron

Molecular Pharmacology September 1982, 22 (2) 298-303;
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Cholinergic muscarinic receptor in synaptosomal membranes. Heterogeneity of binding sites for L-[3H]quinuclidinyl benzilate.
J S Aguilar, P J Salas and E De Robertis

Molecular Pharmacology September 1982, 22 (2) 304-309;
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Muscarinic cholinergic receptor-mediated activation of phosphodiesterase.
R B Meeker and T K Harden

Molecular Pharmacology September 1982, 22 (2) 310-319;
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Guanine nucleotides and monovalent cations increase agonist affinity of prostaglandin E2 receptors in hamster adipocytes.
R Grandt, K Aktories and K H Jakobs

Molecular Pharmacology September 1982, 22 (2) 320-326;
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gamma-aminobutyric acid receptors modulate cation binding sites coupled to independent benzodiazepine, picrotoxin, and anion binding sites.
R F Squires and E Saederup

Molecular Pharmacology September 1982, 22 (2) 327-334;
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Thermodynamic changes associated with benzodiazepine and alkyl beta-carboline-3-carboxylate binding to rat brain homogenates.
R L Kochman and J D Hirsch

Molecular Pharmacology September 1982, 22 (2) 335-341;
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Thermodependence of guanine nucleotide-activated rat cardiac adenylate cyclase activity. Effect of cholera toxin pretreatment.
P Chatelain, P Robberecht, M Waelbroeck, P De Neef, J Camus and J Christophe

Molecular Pharmacology September 1982, 22 (2) 342-348;
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An analysis of binding at the opioid receptor based upon an agonist/antagonist two-state model.
B V Cheney, R A Lahti, C Barsuhn and D D Gay

Molecular Pharmacology September 1982, 22 (2) 349-359;
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The effects of exposure to unsaturated fatty acids on opiate receptors, prostaglandin E1 receptors, and adenylate cyclase activity of neuroblastoma x glioma hybrid cells.
R McGee and J G Kenimer

Molecular Pharmacology September 1982, 22 (2) 360-368;
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Modification of dose-response curves by effector blockade and uncompetitive antagonism.
P Pennefather and D M Quastel

Molecular Pharmacology September 1982, 22 (2) 369-380;
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Oxytocin action. Mechanisms for insulin-like activity in isolated rat adipocytes.
K Hanif, H J Goren, M D Hollenberg and K Lederis

Molecular Pharmacology September 1982, 22 (2) 381-388;
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Effects of acute and chronic morphine treatment of calmodulin activity of rat brain.
R Nehmad, H Nadler and R Simantov

Molecular Pharmacology September 1982, 22 (2) 389-394;
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Calmodulin inhibitors activate glycogen phosphorylase B to A conversion in C6 glioma cells.
J A Norman and M Staehelin

Molecular Pharmacology September 1982, 22 (2) 395-402;
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Hydrophobic interaction of the Ca2+-calmodulin complex with calmodulin antagonists. Naphthalenesulfonamide derivatives.
T Tanaka, T Ohmura and H Hidaka

Molecular Pharmacology September 1982, 22 (2) 403-407;
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Two types of calcium-dependent protein phosphorylations modulated by calmodulin antagonists. Naphthalenesulfonamide derivatives.
T Tanaka, T Ohmura, T Yamakado and H Hidaka

Molecular Pharmacology September 1982, 22 (2) 408-412;
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Effects of microtubular inhibitors on plasma membrane calmodulin-dependent Ca2+-transport ATPase.
K Gietzen, A Wüthrich and H Bader

Molecular Pharmacology September 1982, 22 (2) 413-420;
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Induction of tyrosine hydroxylase by glucocorticoids in mouse neuroblastoma cells. Enhancement of the induction by cyclic AMP.
A W Tank and N Weiner

Molecular Pharmacology September 1982, 22 (2) 421-430;
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Comparison of epileptogenic properties of unsubstituted and beta-alkyl-substituted gamma-butyrolactones.
W E Klunk, D F Covey and J A Ferrendelli

Molecular Pharmacology September 1982, 22 (2) 431-437;
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Anticonvulsant properties of alpha, gamma, and alpha, gamma-substituted gamma-butyrolactones.
W E Klunk, D F Covey and J A Ferrendelli

Molecular Pharmacology September 1982, 22 (2) 438-443;
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Structure-activity relationships of alkyl-substituted gamma-butyrolactones and succinimides.
W E Klunk, D F Covey and J A Ferrendelli

Molecular Pharmacology September 1982, 22 (2) 444-450;
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Kinetic determinants of benzo[a]pyrene metabolism to dihydrodiol epoxides by 3-methylcholanthrene-induced rat liver microsomes.
G M Keller, C R Turner and C R Jefcoate

Molecular Pharmacology September 1982, 22 (2) 451-458;
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Molecular orbital studies of epoxide stability of carcinogenic polycyclic aromatic hydrocarbon diol epoxides.
S M Adams and L S Kaminsky

Molecular Pharmacology September 1982, 22 (2) 459-464;
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The opposing effects of N-hydroxyamphetamine and N-hydroxyphentermine on the H2O2 generated by hepatic cytochrome P-450.
A K Cho, M S Maynard, R M Matsumoto, B Lindeke, U Paulsen and G T Miwa

Molecular Pharmacology September 1982, 22 (2) 465-470;
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Inhibition of microsomal oxidative drug metabolism by 1,4-bis (2-[(2-hydroxyethyl)amino]-ethylamino)-9,10-anthracenedione diacetate, a new antineoplastic agent.
E D Kharasch and R F Novak

Molecular Pharmacology September 1982, 22 (2) 471-478;
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Prostaglandin synthetase-catalyzed activation of phenacetin metabolites to genotoxic products.
B Andersson, M Nordenskjöld, A Rahimtula and P Moldéus

Molecular Pharmacology September 1982, 22 (2) 479-485;
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Comparison of the in vivo and in vitro antileukemic activity of monosubstituted derivatives of 4'-(9-acridinylamino)methanesulfon-m-anisidide.
B C Baguley and B F Cain

Molecular Pharmacology September 1982, 22 (2) 486-492;
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Catecholamine-induced release of the folic acid analogue, methotrexate, from rat hepatocytes in suspension. An alpha-adrenergic phenomenon.
D A Gewirtz, J K Randolph and I D Goldman

Molecular Pharmacology September 1982, 22 (2) 493-499;
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A monoclonal antibody elicited to human platelet monoamine oxidase. Isolation and specificity for human monoamine oxidase B but not A.
R M Denney, N T Patel, R R Fritz and C W Abell

Molecular Pharmacology September 1982, 22 (2) 500-508;
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Rates of sulfation and glucuronidation of 7-hydroxycoumarin in periportal and pericentral regions of the liver lobule.
J G Conway, F C Kauffman, S Ji and R G Thurman

Molecular Pharmacology September 1982, 22 (2) 509-516;
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Effects of adenine nucleosides on RNA synthesis in adenovirus-infected cells. 9-beta-D-Arabinofuranosyladenine as a selective inhibitor of RNA polyadenylation.
K M Rose, T B Leonard and T H Carter

Molecular Pharmacology September 1982, 22 (2) 517-523;