Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole.

J M Woynarowski; M McHugh; R D Sigmund; T A Beerman

Article Information

vol. 35 no. 2 177-182

PubMed

2465485

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0026-895X

Online ISSN

1521-0111

History

Published online February 1, 1989.

Author Information

J M Woynarowski,
M McHugh,
R D Sigmund and
T A Beerman

Grace Cancer Drug Center, Roswell Park Memorial Institute, Buffalo, New York 14263.

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Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole.

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Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole.

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Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole.

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Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole.

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Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole.

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