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Table of Contents

February 01, 1992; Volume 41,Issue 2

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Chloride transport blockers prevent N-methyl-D-aspartate receptor-channel complex activation.
J Lerma and R Martín del Río

Molecular Pharmacology February 1992, 41 (2) 217-222;
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Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: implications for antisense technology.
W Y Gao, F S Han, C Storm, W Egan and Y C Cheng

Molecular Pharmacology February 1992, 41 (2) 223-229;
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Expression of human mu or alpha class glutathione S-transferases in stably transfected human MCF-7 breast cancer cells: effect on cellular sensitivity to cytotoxic agents.
A J Townsend, C P Tu and K H Cowan

Molecular Pharmacology February 1992, 41 (2) 230-236;
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Topoisomerase II-mediated DNA cleavage activity and irreversibility of cleavable complex formation induced by DNA intercalator with alkylating capability.
X B Kong, L Rubin, L I Chen, G Ciszewska, K A Watanabe, W P Tong, F M Sirotnak and T C Chou

Molecular Pharmacology February 1992, 41 (2) 237-244;
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Incorporation of the carbocyclic analog of 2'-deoxyguanosine into the DNA of herpes simplex virus and of HEp-2 cells infected with herpes simplex virus.
W B Parker, S C Shaddix, P W Allan, G Arnett, L M Rose, W M Shannon, Y F Shealy, J A Montgomery, J A Secrist and L L Bennett

Molecular Pharmacology February 1992, 41 (2) 245-251;
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Comparative effects of 3'-azido-3'-deoxythymidine and its metabolite 3'-amino-3'-deoxythymidine on hemoglobin synthesis in K-562 human leukemia cells.
D A Weidner, E G Bridges, E M Cretton and J P Sommadossi

Molecular Pharmacology February 1992, 41 (2) 252-258;
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Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.
R Hyland, A Gescher, K Thummel, C Schiller, P Jheeta, K Mynett, A W Smith and J Mráz

Molecular Pharmacology February 1992, 41 (2) 259-266;
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5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors.
J A Mancini, P Prasit, M G Coppolino, P Charleson, S Leger, J F Evans, J W Gillard and P J Vickers

Molecular Pharmacology February 1992, 41 (2) 267-272;
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Specific antibodies against Go isoforms reveal the early expression of the Go2 alpha subunit and appearance of Go1 alpha during neuronal differentiation.
B Rouot, N Charpentier, C Chabbert, J Carrette, R Zumbihl, J Bockaert and V Homburger

Molecular Pharmacology February 1992, 41 (2) 273-280;
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Platelet-activating factor stimulates phosphoinositide turnover in neurohybrid NCB-20 cells: involvement of pertussis toxin-sensitive guanine nucleotide-binding proteins and inhibition by protein kinase C.
T L Yue, J M Stadel, H M Sarau, E Friedman, J L Gu, D A Powers, M M Gleason, G Feuerstein and H Y Wang

Molecular Pharmacology February 1992, 41 (2) 281-289;
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Heterogeneity of angiotensin II AT2 receptors in the rat brain.
K Tsutsumi and J M Saavedra

Molecular Pharmacology February 1992, 41 (2) 290-297;
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[35S]sadopine, a novel high affinity, high specific activity, L-type Ca2+ channel probe: characterization of two equipotent diastereomers with opposite allosteric properties.
H G Knaus, J Striessnig, S Hering, S Marrer, E Schwenner, H D Höltje and H Glossmann

Molecular Pharmacology February 1992, 41 (2) 298-307;
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Stimulation of N-methyl-D-aspartate receptor-mediated calcium entry into dissociated neurons by reduced and oxidized glutathione.
S W Leslie, L M Brown, R D Trent, Y H Lee, J L Morris, T W Jones, P K Randall, S S Lau and T J Monks

Molecular Pharmacology February 1992, 41 (2) 308-314;
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Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
R P Mason, D M Moisey and L Shajenko

Molecular Pharmacology February 1992, 41 (2) 315-321;
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Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel.
J Snyders, K M Knoth, S L Roberds and M M Tamkun

Molecular Pharmacology February 1992, 41 (2) 322-330;
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Modulation of phencyclidine-sensitive ethidium binding to the Torpedo acetylcholine receptor: interaction of noncompetitive inhibitors with carbamylcholine and cobra alpha-toxin.
C F Valenzuela, J A Kerr, P Duvvuri and D A Johnson

Molecular Pharmacology February 1992, 41 (2) 331-336;
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Quinoxaline derivatives: structure-activity relationships and physiological implications of inhibition of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated currents and synaptic potentials.
J C Randle, T Guet, C Bobichon, C Moreau, P Curutchet, B Lambolez, L P de Carvalho, A Cordi and J M Lepagnol

Molecular Pharmacology February 1992, 41 (2) 337-345;
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Serotonin increases calcium current in human atrial myocytes via the newly described 5-hydroxytryptamine4 receptors.
H Ouadid, J Seguin, A Dumuis, J Bockaert and J Nargeot

Molecular Pharmacology February 1992, 41 (2) 346-351;
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A2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase.
I Hide, W L Padgett, K A Jacobson and J W Daly

Molecular Pharmacology February 1992, 41 (2) 352-359;
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Interaction of aminoalkylcarbamates of forskolin with adenylyl cyclase: synthesis of an iodinated derivative of forskolin with high affinity for adenylyl cyclase.
A Laurenza, J D Robbins and K B Seamon

Molecular Pharmacology February 1992, 41 (2) 360-368;
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Structural basis of the subtype selectivity of muscarinic antagonists: a study with chimeric m2/m5 muscarinic receptors.
J Wess, D Gdula and M R Brann

Molecular Pharmacology February 1992, 41 (2) 369-374;
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Isoproterenol-initiated beta-adrenergic receptor diacytosis in cultured cells.
J B Kurz and J P Perkins

Molecular Pharmacology February 1992, 41 (2) 375-381;
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Quantitative analysis of diacylglycerol second messengers in human platelets: correlation with aggregation and secretion.
M H Werner, A E Bielawska and Y A Hannun

Molecular Pharmacology February 1992, 41 (2) 382-386;
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Kinetic analysis of protein kinase C inhibition by staurosporine: evidence that inhibition entails inhibitor binding at a conserved region of the catalytic domain but not competition with substrates.
N E Ward and C A O'Brian

Molecular Pharmacology February 1992, 41 (2) 387-392;
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Enhancement of adipocyte differentiation by an insulin-sensitizing agent.
R F Kletzien, S D Clarke and R G Ulrich

Molecular Pharmacology February 1992, 41 (2) 393-398;
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Characterization of endothelin-converting enzyme from endothelial cells and rat brain: detection of the formation of biologically active endothelin-1 by rapid bioassay.
T D Warner, J A Mitchell, P D'Orleans-Juste, K Ishii, U Förstermann and F Murad

Molecular Pharmacology February 1992, 41 (2) 399-403;
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Lactosylated high density lipoprotein: a potential carrier for the site-specific delivery of drugs to parenchymal liver cells.
M K Bijsterbosch and T J Van Berkel

Molecular Pharmacology February 1992, 41 (2) 404-411;
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Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase.
H A Berman and K Leonard

Molecular Pharmacology February 1992, 41 (2) 412-418;
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Direct measurements of the rate constants of sulfonamides with carbonic anhydrase.
T H Maren

Molecular Pharmacology February 1992, 41 (2) 419-426;
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Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal.
E S Roberts, A D Vaz and M J Coon

Molecular Pharmacology February 1992, 41 (2) 427-433;