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Molecular Pharmacology

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Table of Contents

April 01, 1994; Volume 45,Issue 4
  • You have access
    Epibatidine, a potent analgetic and nicotinic agonist.
    B Badio and J W Daly
    Molecular Pharmacology April 1994, 45 (4) 563-569;
  • You have access
    Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures.
    L Prézeau, J Carrette, B Helpap, K Curry, J P Pin and J Bockaert
    Molecular Pharmacology April 1994, 45 (4) 570-577;
  • You have access
    The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.
    R Seifert, A Hagelüken, A Höer, D Höer, L Grünbaum, S Offermanns, I Schwaner, V Zingel, W Schunack and G Schultz
    Molecular Pharmacology April 1994, 45 (4) 578-586;
  • You have access
    Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.
    S F Law, S Zaina, R Sweet, K Yasuda, G I Bell, J Stadel and T Reisine
    Molecular Pharmacology April 1994, 45 (4) 587-590;
  • You have access
    Increased voltage-dependent calcium influx produced by alpha 1B-adrenergic receptor activation in rat medullary thyroid carcinoma 6-23 cells.
    T A Esbenshade, T L Theroux and K P Minneman
    Molecular Pharmacology April 1994, 45 (4) 591-598;
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    Photoaffinity labeling of rat pancreatic cholecystokinin type A receptor antagonist binding sites demonstrates the presence of a truncated cholecystokinin type A receptor.
    S S Poirot, C Escrieut, M Dufresne, J Martinez, M Bouisson, N Vaysse and D Fourmy
    Molecular Pharmacology April 1994, 45 (4) 599-607;
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    Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.
    K M Kim, S F Kingsmore, H Han, T L Yang-Feng, N Godinot, M F Seldin, M G Caron and B Giros
    Molecular Pharmacology April 1994, 45 (4) 608-617;
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    Chronic benzodiazepine agonist treatment produces functional uncoupling of the gamma-aminobutyric acid-benzodiazepine receptor ionophore complex in cortical neurons.
    X J Hu and M K Ticku
    Molecular Pharmacology April 1994, 45 (4) 618-625;
  • You have access
    Metabotropic glutamate receptor heterogeneity in rat brain.
    M V Catania, H De Socarraz, J B Penney and A B Young
    Molecular Pharmacology April 1994, 45 (4) 626-636;
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    Quantitative changes in alpha 1 and alpha 5 gamma-aminobutyric acid type A receptor subunit mRNAs and proteins after a single treatment of cerebellar granule neurons with N-methyl-D-aspartate.
    B T Harris, M E Charlton, E Costa and D R Grayson
    Molecular Pharmacology April 1994, 45 (4) 637-648;
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    Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells.
    F A Fornari, J K Randolph, J C Yalowich, M K Ritke and D A Gewirtz
    Molecular Pharmacology April 1994, 45 (4) 649-656;
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    Reduced expression of gamma-aminobutyric acid type A/benzodiazepine receptor gamma 2 and alpha 5 subunit mRNAs in brain regions of flurazepam-treated rats.
    T J Zhao, T H Chiu and H C Rosenberg
    Molecular Pharmacology April 1994, 45 (4) 657-663;
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    Metabolism and cytotoxicity of naphthalene and its metabolites in isolated murine Clara cells.
    C H Chichester, A R Buckpitt, A Chang and C G Plopper
    Molecular Pharmacology April 1994, 45 (4) 664-672;
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    Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program.
    I Posner, M Engel, A Gazit and A Levitzki
    Molecular Pharmacology April 1994, 45 (4) 673-683;
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    Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific.
    E Falck-Pedersen, M Heinflink, M Alvira, D R Nussenzveig and M C Gershengorn
    Molecular Pharmacology April 1994, 45 (4) 684-689;
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    Localization of the ligand binding site of the neurokinin-1 receptor: interpretation of chimeric mutations and single-residue substitutions.
    R R Huang, H Yu, C D Strader and T M Fong
    Molecular Pharmacology April 1994, 45 (4) 690-695;
  • You have access
    Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs.
    M G Eason, M T Jacinto and S B Liggett
    Molecular Pharmacology April 1994, 45 (4) 696-702;
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    The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.
    C Forray, J A Bard, J M Wetzel, G Chiu, E Shapiro, R Tang, H Lepor, P R Hartig, R L Weinshank and T A Branchek
    Molecular Pharmacology April 1994, 45 (4) 703-708;
  • You have access
    Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors.
    J Proska and S Tucek
    Molecular Pharmacology April 1994, 45 (4) 709-717;
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    Identification and characterization of a lysophosphatidic acid receptor.
    F J Thomson, L Perkins, D Ahern and M Clark
    Molecular Pharmacology April 1994, 45 (4) 718-723;
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    RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin.
    T Tanaka, E Tsukuda, M Nozawa, H Nonaka, T Ohno, H Kase, K Yamada and Y Matsuda
    Molecular Pharmacology April 1994, 45 (4) 724-730;
  • You have access
    Differential heterologous and homologous desensitization of two receptors for ATP (P2y purinoceptors and nucleotide receptors) coexisting on endothelial cells.
    G F Wilkinson, J R Purkiss and M R Boarder
    Molecular Pharmacology April 1994, 45 (4) 731-736;
  • You have access
    Docosahexaenoic acid and signaling pathways in rabbit colon.
    V Calderaro, C Parrillo, M L Balestrieri, A Giovane, A Filippelli and F Rossi
    Molecular Pharmacology April 1994, 45 (4) 737-746;
  • You have access
    Loperamide blocks high-voltage-activated calcium channels and N-methyl-D-aspartate-evoked responses in rat and mouse cultured hippocampal pyramidal neurons.
    J Church, E J Fletcher, K Abdel-Hamid and J F MacDonald
    Molecular Pharmacology April 1994, 45 (4) 747-757;
  • You have access
    The beta subunit of neuronal nicotinic acetylcholine receptors is a determinant of the affinity for substance P inhibition.
    G A Stafford, R E Oswald and G A Weiland
    Molecular Pharmacology April 1994, 45 (4) 758-762;
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    Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates.
    W D Stein, C Cardarelli, I Pastan and M M Gottesman
    Molecular Pharmacology April 1994, 45 (4) 763-772;
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    Direct demonstration of high affinity interactions of immunosuppressant drugs with the drug binding site of the human P-glycoprotein.
    U S Rao and G A Scarborough
    Molecular Pharmacology April 1994, 45 (4) 773-776;
  • You have access
    Effects of IMP dehydrogenase inhibitors on the phosphorylation of ganciclovir in MOLT-4 cells before and after herpes simplex virus thymidine kinase gene transduction.
    R Agbaria, C A Mullen, N R Hartman, D A Cooney, Z Hao, R M Blaese and D G Johns
    Molecular Pharmacology April 1994, 45 (4) 777-782;
  • You have access
    Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    M S Rhee, J Galivan, J E Wright and A Rosowsky
    Molecular Pharmacology April 1994, 45 (4) 783-791;
  • You have access
    p-Alkoxyphenols, a new class of inhibitors of mammalian R2 ribonucleotide reductase: possible candidates for antimelanotic drugs.
    S Pötsch, H Drechsler, B Liermann, A Gräslund and G Lassmann
    Molecular Pharmacology April 1994, 45 (4) 792-796;
  • You have access
    Aldose reductase-catalyzed reduction of acrolein: implications in cyclophosphamide toxicity.
    N S Kolb, L A Hunsaker and D L Vander Jagt
    Molecular Pharmacology April 1994, 45 (4) 797-801;
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In this issue

Molecular Pharmacology
Vol. 45, Issue 4
1 Apr 1994
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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