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Table of Contents

April 01, 1994; Volume 45,Issue 4

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Epibatidine, a potent analgetic and nicotinic agonist.
B Badio and J W Daly

Molecular Pharmacology April 1994, 45 (4) 563-569;
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Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures.
L Prézeau, J Carrette, B Helpap, K Curry, J P Pin and J Bockaert

Molecular Pharmacology April 1994, 45 (4) 570-577;
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The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.
R Seifert, A Hagelüken, A Höer, D Höer, L Grünbaum, S Offermanns, I Schwaner, V Zingel, W Schunack and G Schultz

Molecular Pharmacology April 1994, 45 (4) 578-586;
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Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.
S F Law, S Zaina, R Sweet, K Yasuda, G I Bell, J Stadel and T Reisine

Molecular Pharmacology April 1994, 45 (4) 587-590;
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Increased voltage-dependent calcium influx produced by alpha 1B-adrenergic receptor activation in rat medullary thyroid carcinoma 6-23 cells.
T A Esbenshade, T L Theroux and K P Minneman

Molecular Pharmacology April 1994, 45 (4) 591-598;
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Photoaffinity labeling of rat pancreatic cholecystokinin type A receptor antagonist binding sites demonstrates the presence of a truncated cholecystokinin type A receptor.
S S Poirot, C Escrieut, M Dufresne, J Martinez, M Bouisson, N Vaysse and D Fourmy

Molecular Pharmacology April 1994, 45 (4) 599-607;
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Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.
K M Kim, S F Kingsmore, H Han, T L Yang-Feng, N Godinot, M F Seldin, M G Caron and B Giros

Molecular Pharmacology April 1994, 45 (4) 608-617;
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Chronic benzodiazepine agonist treatment produces functional uncoupling of the gamma-aminobutyric acid-benzodiazepine receptor ionophore complex in cortical neurons.
X J Hu and M K Ticku

Molecular Pharmacology April 1994, 45 (4) 618-625;
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Metabotropic glutamate receptor heterogeneity in rat brain.
M V Catania, H De Socarraz, J B Penney and A B Young

Molecular Pharmacology April 1994, 45 (4) 626-636;
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Quantitative changes in alpha 1 and alpha 5 gamma-aminobutyric acid type A receptor subunit mRNAs and proteins after a single treatment of cerebellar granule neurons with N-methyl-D-aspartate.
B T Harris, M E Charlton, E Costa and D R Grayson

Molecular Pharmacology April 1994, 45 (4) 637-648;
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Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells.
F A Fornari, J K Randolph, J C Yalowich, M K Ritke and D A Gewirtz

Molecular Pharmacology April 1994, 45 (4) 649-656;
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Reduced expression of gamma-aminobutyric acid type A/benzodiazepine receptor gamma 2 and alpha 5 subunit mRNAs in brain regions of flurazepam-treated rats.
T J Zhao, T H Chiu and H C Rosenberg

Molecular Pharmacology April 1994, 45 (4) 657-663;
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Metabolism and cytotoxicity of naphthalene and its metabolites in isolated murine Clara cells.
C H Chichester, A R Buckpitt, A Chang and C G Plopper

Molecular Pharmacology April 1994, 45 (4) 664-672;
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Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program.
I Posner, M Engel, A Gazit and A Levitzki

Molecular Pharmacology April 1994, 45 (4) 673-683;
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Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific.
E Falck-Pedersen, M Heinflink, M Alvira, D R Nussenzveig and M C Gershengorn

Molecular Pharmacology April 1994, 45 (4) 684-689;
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Localization of the ligand binding site of the neurokinin-1 receptor: interpretation of chimeric mutations and single-residue substitutions.
R R Huang, H Yu, C D Strader and T M Fong

Molecular Pharmacology April 1994, 45 (4) 690-695;
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Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs.
M G Eason, M T Jacinto and S B Liggett

Molecular Pharmacology April 1994, 45 (4) 696-702;
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The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.
C Forray, J A Bard, J M Wetzel, G Chiu, E Shapiro, R Tang, H Lepor, P R Hartig, R L Weinshank and T A Branchek

Molecular Pharmacology April 1994, 45 (4) 703-708;
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Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors.
J Proska and S Tucek

Molecular Pharmacology April 1994, 45 (4) 709-717;
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Identification and characterization of a lysophosphatidic acid receptor.
F J Thomson, L Perkins, D Ahern and M Clark

Molecular Pharmacology April 1994, 45 (4) 718-723;
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RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin.
T Tanaka, E Tsukuda, M Nozawa, H Nonaka, T Ohno, H Kase, K Yamada and Y Matsuda

Molecular Pharmacology April 1994, 45 (4) 724-730;
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Differential heterologous and homologous desensitization of two receptors for ATP (P2y purinoceptors and nucleotide receptors) coexisting on endothelial cells.
G F Wilkinson, J R Purkiss and M R Boarder

Molecular Pharmacology April 1994, 45 (4) 731-736;
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Docosahexaenoic acid and signaling pathways in rabbit colon.
V Calderaro, C Parrillo, M L Balestrieri, A Giovane, A Filippelli and F Rossi

Molecular Pharmacology April 1994, 45 (4) 737-746;
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Loperamide blocks high-voltage-activated calcium channels and N-methyl-D-aspartate-evoked responses in rat and mouse cultured hippocampal pyramidal neurons.
J Church, E J Fletcher, K Abdel-Hamid and J F MacDonald

Molecular Pharmacology April 1994, 45 (4) 747-757;
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The beta subunit of neuronal nicotinic acetylcholine receptors is a determinant of the affinity for substance P inhibition.
G A Stafford, R E Oswald and G A Weiland

Molecular Pharmacology April 1994, 45 (4) 758-762;
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Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates.
W D Stein, C Cardarelli, I Pastan and M M Gottesman

Molecular Pharmacology April 1994, 45 (4) 763-772;
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Direct demonstration of high affinity interactions of immunosuppressant drugs with the drug binding site of the human P-glycoprotein.
U S Rao and G A Scarborough

Molecular Pharmacology April 1994, 45 (4) 773-776;
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Effects of IMP dehydrogenase inhibitors on the phosphorylation of ganciclovir in MOLT-4 cells before and after herpes simplex virus thymidine kinase gene transduction.
R Agbaria, C A Mullen, N R Hartman, D A Cooney, Z Hao, R M Blaese and D G Johns

Molecular Pharmacology April 1994, 45 (4) 777-782;
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Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
M S Rhee, J Galivan, J E Wright and A Rosowsky

Molecular Pharmacology April 1994, 45 (4) 783-791;
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p-Alkoxyphenols, a new class of inhibitors of mammalian R2 ribonucleotide reductase: possible candidates for antimelanotic drugs.
S Pötsch, H Drechsler, B Liermann, A Gräslund and G Lassmann

Molecular Pharmacology April 1994, 45 (4) 792-796;
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Aldose reductase-catalyzed reduction of acrolein: implications in cyclophosphamide toxicity.
N S Kolb, L A Hunsaker and D L Vander Jagt

Molecular Pharmacology April 1994, 45 (4) 797-801;