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Abstract

Binding of [26-3H]bryostatin 1 and analogs to calcium-dependent and calcium-independent protein kinase C isozymes.

M G Kazanietz, N E Lewin, F Gao, G R Pettit and P M Blumberg
Molecular Pharmacology August 1994, 46 (2) 374-379;

Abstract

In this study we explored the pattern of protein kinase C (PKC) isozyme selectivity of the bryostatins, a unique class of PKC activators that induce only a subset of the typical phorbol ester