RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.

A P Ford; N F Arredondo; D R Blue; D W Bonhaus; J Jasper; M S Kava; J Lesnick; J R Pfister; I A Shieh; R L Vimont; T J Williams; J E McNeal; T A Stamey; D E Clarke

Abstract

RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.

A P Ford, N F Arredondo, D R Blue Jr, D W Bonhaus, J Jasper, M S Kava, J Lesnick, J R Pfister, I A Shieh, R L Vimont, T J Williams, J E McNeal, T A Stamey and D E Clarke

Molecular Pharmacology February 1996, 49 (2) 209-215;

A P Ford

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N F Arredondo

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D R Blue Jr

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D W Bonhaus

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J Jasper

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M S Kava

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J Lesnick

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J R Pfister

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I A Shieh

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R L Vimont

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T J Williams

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J E McNeal

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T A Stamey

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D E Clarke

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Molecular Pharmacology

Vol. 49, Issue 2

1 Feb 1996

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Abstract

RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.

A P Ford, N F Arredondo, D R Blue, D W Bonhaus, J Jasper, M S Kava, J Lesnick, J R Pfister, I A Shieh, R L Vimont, T J Williams, J E McNeal, T A Stamey and D E Clarke

Molecular Pharmacology February 1, 1996, 49 (2) 209-215;

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Abstract

RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.

A P Ford, N F Arredondo, D R Blue, D W Bonhaus, J Jasper, M S Kava, J Lesnick, J R Pfister, I A Shieh, R L Vimont, T J Williams, J E McNeal, T A Stamey and D E Clarke

Molecular Pharmacology February 1, 1996, 49 (2) 209-215;

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