Molecular Pharmacology: 50 (5)

November 01, 1996; Volume 50,Issue 5

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Differences in the inhibition of human immunodeficiency virus type 1 reverse transcriptase DNA polymerase activity by analogs of nevirapine and [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1", 2"-oxathiole-2",2"-dioxide] (TSAO).
D Arion, R S Fletcher, G Borkow, M J Camarasa, J Balzarini, G I Dmitrienko and M A Parniak

Molecular Pharmacology November 1996, 50 (5) 1057-1064;
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Induction of cytochrome P450 2E1 expression in rat and gerbil astrocytes by inflammatory factors and ischemic injury.
N Tindberg, H A Baldwin, A J Cross and M Ingelman-Sundberg

Molecular Pharmacology November 1996, 50 (5) 1065-1072;
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Changes of D1 and D2 dopamine receptor mRNA in the brains of monkeys lesioned with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: correction with chronic administration of L-3,4-dihydroxyphenylalanine.
M Morissette, M Goulet, F Calon, P Falardeau, P J Blanchet, P J Bédard and T Di Paolo

Molecular Pharmacology November 1996, 50 (5) 1073-1079;
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Isolation and characterization of a cisplatin-resistant strain of Schizosaccharomyces pombe.
P Perego, G Jimenez and S B Howell

Molecular Pharmacology November 1996, 50 (5) 1080-1086;
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Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells.
J M Gimble, C E Robinson, X Wu, K A Kelly, B R Rodriguez, S A Kliewer, J M Lehmann and D C Morris

Molecular Pharmacology November 1996, 50 (5) 1087-1094;
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Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA.
J L Nitiss and J C Wang

Molecular Pharmacology November 1996, 50 (5) 1095-1102;
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Differential regulation of corticotropin-releasing factor1 receptor expression by stress and agonist treatments in brain and cultured cells.
P A Iredale, R Terwilliger, K L Widnell, E J Nestler and R S Duman

Molecular Pharmacology November 1996, 50 (5) 1103-1110;
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CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance.
D C Zeldin, J Foley, J Ma, J E Boyle, J M Pascual, C R Moomaw, K B Tomer, C Steenbergen and S Wu

Molecular Pharmacology November 1996, 50 (5) 1111-1117;
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Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding.
M M Zhao, J Hwa and D M Perez

Molecular Pharmacology November 1996, 50 (5) 1118-1126;
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Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages.
K S Selander, J Mönkkönen, E K Karhukorpi, P Härkönen, R Hannuniemi and H K Väänänen

Molecular Pharmacology November 1996, 50 (5) 1127-1138;
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Involvement of mitogen-activated protein kinase and translocation of cytosolic phospholipase A2 to the nuclear envelope in acetylcholine-induced prostacyclin synthesis in rabbit coronary endothelial cells.
H Kan, Y Ruan and K U Malik

Molecular Pharmacology November 1996, 50 (5) 1139-1147;
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Feminization of hepatic cytochrome P450s by nominal levels of growth hormone in the feminine plasma profile.
N A Pampori and B H Shapiro

Molecular Pharmacology November 1996, 50 (5) 1148-1156;
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Rat 17 beta-hydroxysteroid dehydrogenase type IV is a novel peroxisome proliferator-inducible gene.
J C Corton, C Bocos, E S Moreno, A Merritt, D S Marsman, P J Sausen, R C Cattley and J A Gustafsson

Molecular Pharmacology November 1996, 50 (5) 1157-1166;
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Three new toxins from the scorpion Pandinus imperator selectively block certain voltage-gated K+ channels.
R S Rogowski, J H Collins, T J O'Neill, T A Gustafson, T R Werkman, M A Rogawski, T C Tenenholz, D J Weber and M P Blaustein

Molecular Pharmacology November 1996, 50 (5) 1167-1177;
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Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells.
J W Lawrence, D C Claire, V Weissig and T C Rowe

Molecular Pharmacology November 1996, 50 (5) 1178-1188;
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The neurokinin-1 receptor antagonist LY306,740 blocks nociception-induced increases in dorsal horn neurokinin-1 receptor gene expression.
K E McCarson and J E Krause

Molecular Pharmacology November 1996, 50 (5) 1189-1199;
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Novel antagonists of the inhibitory glycine receptor derived from quinolinic acid compounds.
V Schmieden, S Jezequel and H Betz

Molecular Pharmacology November 1996, 50 (5) 1200-1206;
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Antiretrovirus specificity and intracellular metabolism of 2',3' -didehydro-2',3'-dideoxythymidine (stavudine) and its 5'-monophosphate triester prodrug So324.
J Balzarini, H Egberink, K Hartmann, D Cahard, T Vahlenkamp, H Thormar, E De Clercq and C McGuigan

Molecular Pharmacology November 1996, 50 (5) 1207-1213;
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Agonist-induced functional desensitization of the mu-opioid receptor is mediated by loss of membrane receptors rather than uncoupling from G protein.
Y Pak, A Kouvelas, M A Scheideler, J Rasmussen, B F O'Dowd and S R George

Molecular Pharmacology November 1996, 50 (5) 1214-1222;
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Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6 -trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors.
C T Murphy, A J Bullock, C J Lindley, S J Mills, A M Riley, B V Potter and J Westwick

Molecular Pharmacology November 1996, 50 (5) 1223-1230;
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Evidence for distinction of the differentiation-inducing activities and cytostatic properties of 9-(2-phosphonylmethoxyethyl)adenine and a variety of differentiation-inducing agents in human erythroleukemia K562 cells.
S Hatse, E De Clercq and J Balzarini

Molecular Pharmacology November 1996, 50 (5) 1231-1242;
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Pharmacological differentiation between intracellular calcium pump isoforms.
S Engelender and L De Meis

Molecular Pharmacology November 1996, 50 (5) 1243-1252;
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Pharmacological modulation of the diazepam-insensitive recombinant gamma-aminobutyric acidA receptors alpha 4 beta 2 gamma 2 and alpha 6 beta 2 gamma 2.
F Knoflach, D Benke, Y Wang, L Scheurer, H Lüddens, B J Hamilton, D B Carter, H Mohler and J A Benson

Molecular Pharmacology November 1996, 50 (5) 1253-1261;
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Cyclic AMP-independent inhibition of cardiac calcium current by forskolin.
T Asai, S Pelzer and T F McDonald

Molecular Pharmacology November 1996, 50 (5) 1262-1272;
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Membrane-delimited G protein-mediated coupling between V1a vasopressin receptor and dihydropyridine binding sites in rat glomerulosa cells.
E Grazzini, T Durroux, M D Payet, L Bilodeau, N Gallo-Payet and G Guillon

Molecular Pharmacology November 1996, 50 (5) 1273-1283;
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Direct inhibition of 5-hydroxytryptamine3 receptors by antagonists of L-type Ca2+ channels.
A C Hargreaves, M J Gunthorpe, C W Taylor and S C Lummis

Molecular Pharmacology November 1996, 50 (5) 1284-1294;
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Regulation of D2 dopamine receptors by amiloride and amiloride analogs.
S R Hoare and P G Strange

Molecular Pharmacology November 1996, 50 (5) 1295-1308;
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Dopamine induces apoptotic cell death of a catecholaminergic cell line derived from the central nervous system.
J M Masserano, L Gong, H Kulaga, I Baker and R J Wyatt

Molecular Pharmacology November 1996, 50 (5) 1309-1315;
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5-Hydroxytryptamine4 receptors reduce afterhyperpolarization in hippocampus by inhibiting calcium-induced calcium release.
G E Torres, C L Arfken and R Andrade

Molecular Pharmacology November 1996, 50 (5) 1316-1322;
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Identification of competitive antagonists of the P2Y1 receptor.
J L Boyer, T Romero-Avila, J B Schachter and T K Harden

Molecular Pharmacology November 1996, 50 (5) 1323-1329;
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Subunit composition is a major determinant in high affinity binding of a Ca2+ channel blocker.
H Suh-Kim, X Wei and L Birnbaumer

Molecular Pharmacology November 1996, 50 (5) 1330-1337;
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Mutagenesis of residues adjacent to transmembrane prolines alters D1 dopamine receptor binding and signal transduction.
W Cho, L P Taylor and H Akil

Molecular Pharmacology November 1996, 50 (5) 1338-1345;
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Bombesin-like peptide receptor subtypes promote mitogenesis, which requires persistent receptor signaling.
R I Feldman, M F Bartholdi and J M Wu

Molecular Pharmacology November 1996, 50 (5) 1346-1354;
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Discovery of high affinity bombesin receptor subtype 3 agonists.
J M Wu, D E Nitecki, S Biancalana and R I Feldman

Molecular Pharmacology November 1996, 50 (5) 1355-1363;
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Pharmacology of the human gamma-aminobutyric acidA receptor alpha 4 subunit expressed in Xenopus laevis oocytes.
E R Whittemore, W Yang, J A Drewe and R M Woodward

Molecular Pharmacology November 1996, 50 (5) 1364-1375;
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Coupling efficiencies of human alpha 1-adrenergic receptor subtypes: titration of receptor density and responsiveness with inducible and repressible expression vectors.
T L Theroux, T A Esbenshade, R D Peavy and K P Minneman

Molecular Pharmacology November 1996, 50 (5) 1376-1387;
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Distinct effects of mutations in transmembrane segment IVS6 on block of L-type calcium channels by structurally similar phenylalkylamines.
B D Johnson, G H Hockerman, T Scheuer and W A Catterall

Molecular Pharmacology November 1996, 50 (5) 1388-1400;
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Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists.
P C Kearney, M W Nowak, W Zhong, S K Silverman, H A Lester and D A Dougherty

Molecular Pharmacology November 1996, 50 (5) 1401-1412;
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A single residue, Lys108, of the delta-opioid receptor prevents the mu-opioid-selective ligand [D-Ala2,N-MePhe4,Gly-ol5]enkephalin from binding to the delta-opioid receptor.
M Minami, T Nakagawa, T Seki, T Onogi, Y Aoki, Y Katao, S Katsumata and M Satoh

Molecular Pharmacology November 1996, 50 (5) 1413-1422;

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