Molecular Pharmacology: 50 (6)

December 01, 1996; Volume 50,Issue 6

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Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis.
Y Loewenstein-Lichtenstein, D Glick, N Gluzman, M Sternfeld, H Zakut and H Soreq

Molecular Pharmacology December 1996, 50 (6) 1423-1431;
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Analysis of the alpha2C-adrenergic receptor gene promoter and its cell-type-specific activity.
J S Saulnier-Blache, Q Yang, J D Sherlock and S M Lanier

Molecular Pharmacology December 1996, 50 (6) 1432-1442;
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Activation of the skeletal muscle ryanodine receptor by suramin and suramin analogs.
M Hohenegger, M Matyash, K Poussu, A Herrmann-Frank, S Sarközi, F Lehmann-Horn and M Freissmuth

Molecular Pharmacology December 1996, 50 (6) 1443-1453;
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Basis for the loss of aryl hydrocarbon receptor gene expression in clones of a mouse hepatoma cell line.
J Zhang, A J Watson, M R Probst, E Minehart and O Hankinson

Molecular Pharmacology December 1996, 50 (6) 1454-1462;
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Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIalpha (p170) and IIbeta (p180).
M Cornarotti, S Tinelli, E Willmore, F Zunino, L M Fisher, C A Austin and G Capranico

Molecular Pharmacology December 1996, 50 (6) 1463-1471;
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Acquired camptothecin resistance of human breast cancer MCF-7/C4 cells with normal topoisomerase I and elevated DNA repair.
A Fujimori, M Gupta, Y Hoki and Y Pommier

Molecular Pharmacology December 1996, 50 (6) 1472-1478;
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Inverse agonist-induced up-regulation of the human beta2-adrenoceptor in transfected neuroblastoma X glioma hybrid cells.
D J MacEwan and G Milligan

Molecular Pharmacology December 1996, 50 (6) 1479-1486;
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Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine.
A J Stewart, C Pichon, L Meunier, P Midoux, M Monsigny and A C Roche

Molecular Pharmacology December 1996, 50 (6) 1487-1494;
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Inhibition of capacitative Ca2+ entry into cells by farnesylcysteine analogs.
Y Xu, B A Gilbert, R R Rando, L Chen and A H Tashjian

Molecular Pharmacology December 1996, 50 (6) 1495-1501;
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Identification of enzymes catalyzing two-step phosphorylation of cidofovir and the effect of cytomegalovirus infection on their activities in host cells.
T Cihlar and M S Chen

Molecular Pharmacology December 1996, 50 (6) 1502-1510;
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Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2'-NH2-MPTP on serotonergic and noradrenergic nerve terminals.
A M Andrews, B Ladenheim, C J Epstein, J L Cadet and D L Murphy

Molecular Pharmacology December 1996, 50 (6) 1511-1519;
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Effects of volatile anesthetics on the G protein-regulated muscarinic potassium channel.
J Magyar and G Szabo

Molecular Pharmacology December 1996, 50 (6) 1520-1528;
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Transport of adenosine by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from rat jejunum expressed in Xenopus laevis oocytes.
S Y Yao, A M Ng, M W Ritzel, W P Gati, C E Cass and J D Young

Molecular Pharmacology December 1996, 50 (6) 1529-1535;
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Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance.
P A Vasey, N A Jones, S Jenkins, C Dive and R Brown

Molecular Pharmacology December 1996, 50 (6) 1536-1540;
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Subtype-selective inhibition of N-methyl-D-aspartate receptors by haloperidol.
V I Ilyin, E R Whittemore, J Guastella, E Weber and R M Woodward

Molecular Pharmacology December 1996, 50 (6) 1541-1550;
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4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake.
P G Bray, S R Hawley and S A Ward

Molecular Pharmacology December 1996, 50 (6) 1551-1558;
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Physicochemical properties correlated with drug resistance and the reversal of drug resistance in Plasmodium falciparum.
P G Bray, S R Hawley, M Mungthin and S A Ward

Molecular Pharmacology December 1996, 50 (6) 1559-1566;
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Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan.
J E Leysen, W Gommeren, L Heylen, W H Luyten, I Van de Weyer, P Vanhoenacker, G Haegeman, A Schotte, P Van Gompel, R Wouters and A S Lesage

Molecular Pharmacology December 1996, 50 (6) 1567-1580;
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Enantioselectivity of steroid-induced gamma-aminobutyric acidA receptor modulation and anesthesia.
L L Wittmer, Y Hu, M Kalkbrenner, A S Evers, C F Zorumski and D F Covey

Molecular Pharmacology December 1996, 50 (6) 1581-1586;
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Reconstitution of recombinant bovine A1 adenosine receptors in Sf9 cell membranes with recombinant G proteins of defined composition.
R A Figler, S G Graber, M A Lindorfer, H Yasuda, J Linden and J C Garrison

Molecular Pharmacology December 1996, 50 (6) 1587-1595;
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Properties of the pituitary adenylate cyclase-activating polypeptide I and II receptors, vasoactive intestinal peptide1, and chimeric amino-terminal pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal peptide1 receptors: evidence for multiple receptor states.
J Van Rampelbergh, P Gourlet, P De Neef, P Robberecht and M Waelbroeck

Molecular Pharmacology December 1996, 50 (6) 1596-1604;
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Relative contribution of polar interactions and conformational compatibility to the binding of neurokinin-1 receptor antagonists.
T M Fong, H Yu, R R Huang, M A Cascieri and C J Swain

Molecular Pharmacology December 1996, 50 (6) 1605-1611;
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Acid-catalyzed oxidation of the anticancer agent mitoxantrone by nitrite ions.
K J Reszka and C F Chignell

Molecular Pharmacology December 1996, 50 (6) 1612-1618;
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The third extracellular loop of the human delta-opioid receptor determines the selectivity of delta-opioid agonists.
E V Varga, X Li, D Stropova, T Zalewska, R S Landsman, R J Knapp, E Malatynska, K Kawai, A Mizusura, H Nagase, S N Calderon, K Rice, V J Hruby, W R Roeske and H I Yamamura

Molecular Pharmacology December 1996, 50 (6) 1619-1624;
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Evidence for an internal phenylalkylamine action on the voltage-gated potassium channel Kv1.3.
H Rauer and S Grissmer

Molecular Pharmacology December 1996, 50 (6) 1625-1634;
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Site-directed mutagenesis of the human A1 adenosine receptor: influences of acidic and hydroxy residues in the first four transmembrane domains on ligand binding.
H Barbhaiya, R McClain, A Ijzerman and S A Rivkees

Molecular Pharmacology December 1996, 50 (6) 1635-1642;
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The role of inactivation in open-channel block of the sodium channel: studies with inactivation-deficient mutant channels.
A O Grant, J E John, V V Nesterenko, C F Starmer and J R Moorman

Molecular Pharmacology December 1996, 50 (6) 1643-1650;
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Inverse agonistic effect of ICI-174,864 on the cloned delta-opioid receptor: role of G protein and adenylyl cyclase activation.
T T Chiu, L Y Yung and Y H Wong

Molecular Pharmacology December 1996, 50 (6) 1651-1657;
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Identification and pharmacological characterization of [125I]L-750,667, a novel radioligand for the dopamine D4 receptor.
S Patel, S Patel, R Marwood, F Emms, D Marston, P D Leeson, N R Curtis, J J Kulagowski and S B Freedman

Molecular Pharmacology December 1996, 50 (6) 1658-1664;
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Evans blue antagonizes both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate receptors and modulates receptor desensitization.
C J Price and L A Raymond

Molecular Pharmacology December 1996, 50 (6) 1665-1671;
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Novel nonpeptide agents potently block the C-type inactivated conformation of Kv1.3 and suppress T cell activation.
A Nguyen, J C Kath, D C Hanson, M S Biggers, P C Canniff, C B Donovan, R J Mather, M J Bruns, H Rauer, J Aiyar, A Lepple-Wienhues, G A Gutman, S Grissmer, M D Cahalan and K G Chandy

Molecular Pharmacology December 1996, 50 (6) 1672-1679;
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Calcium-dependent inactivation of recombinant N-methyl-D-aspartate receptors is NR2 subunit specific.
J J Krupp, B Vissel, S F Heinemann and G L Westbrook

Molecular Pharmacology December 1996, 50 (6) 1680-1688;

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