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Research ArticleArticle

Dual Agonistic and Antagonistic Property of Nonpeptide Angiotensin AT1 Ligands: Susceptibility to Receptor Mutations

Signe Perlman, Claudio M. Costa-Neto, Ayumi A. Miyakawa, Hans T. Schambye, Siv A. Hjorth, Antonio C. M. Paiva, Ralph A. Rivero, William J. Greenlee and Thue W. Schwartz
Molecular Pharmacology February 1997, 51 (2) 301-311; DOI: https://doi.org/10.1124/mol.51.2.301

Article Information

vol. 51 no. 2 301-311
DOI 
https://doi.org/10.1124/mol.51.2.301
PubMed 
9203636
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received July 8, 1996
  • Accepted November 6, 1996
  • Published online February 1, 1997.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Signe Perlman1,
  2. Claudio M. Costa-Neto1,3,
  3. Ayumi A. Miyakawa1,3,
  4. Hans T. Schambye1,
  5. Siv A. Hjorth1,
  6. Antonio C. M. Paiva3,
  7. Ralph A. Rivero2,
  8. William J. Greenlee2, and
  9. Thue W. Schwartz1,4
  1. 1Laboratory for Molecular Pharmacology, University Department of Clinical Pharmacology, Rigshospitalet, DK-2100, Copenhagen, Denmark (S.P., C.M.C.-M., A.A.M., H.T.S., S.A.H., T.W.S.), 2Department of Exploratory Chemistry, Merck Research Laboratories, Rahway, New Jersey 07065 (R.A.R., W.J.G.), 3Department of Biophysics, Escola Paulista de Medicina, UNIFESP, Sāo Paulo 04023–062, Brazil (C.M.C.-M., A.A.M., A.C.M.P.), and 4Department of Protein Chemistry, Institute of Molecular Biology, University of Copenhagen, DK-1353, Copenhagen, Denmark (T.W.S.)
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Research ArticleArticle

Dual Agonistic and Antagonistic Property of Nonpeptide Angiotensin AT1 Ligands: Susceptibility to Receptor Mutations

Signe Perlman, Claudio M. Costa-Neto, Ayumi A. Miyakawa, Hans T. Schambye, Siv A. Hjorth, Antonio C. M. Paiva, Ralph A. Rivero, William J. Greenlee and Thue W. Schwartz
Molecular Pharmacology February 1, 1997, 51 (2) 301-311; DOI: https://doi.org/10.1124/mol.51.2.301
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