Table of Contents

Articles

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  Mutations in the Sixth Transmembrane Domain of P-Glycoprotein that Alter the Pattern of Cross-resistance Also Alter Sensitivity to Cyclosporin A Reversal

  Jian Feng Ma, Geraldine Grant and Peter W. Melera

  Molecular Pharmacology June 1997, 51 (6) 922-930; DOI: https://doi.org/10.1124/mol.51.6.922
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  CYP2J Subfamily Cytochrome P450s in the Gastrointestinal Tract: Expression, Localization, and Potential Functional Significance

  Darryl C. Zeldin, Julie Foley, Susan M. Goldsworthy, Molly E. Cook, James E. Boyle, Jixiang Ma, Cindy R. Moomaw, Kenneth B. Tomer, Charles Steenbergen and Shu Wu

  Molecular Pharmacology June 1997, 51 (6) 931-943; DOI: https://doi.org/10.1124/mol.51.6.931
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  Gadolinium Chloride Blocks Alcohol-Dependent Liver Toxicity in Rats Treated Chronically with Intragastric Alcohol Despite the Induction of CYP2E1

  Dennis R. Koop, Bethany Klopfenstein, Yuji Iimuro and Ronald G. Thurman

  Molecular Pharmacology June 1997, 51 (6) 944-950; DOI: https://doi.org/10.1124/mol.51.6.944
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  2-Methoxyestradiol, an Endogenous Estrogen Metabolite, Induces Apoptosis in Endothelial Cells and Inhibits Angiogenesis: Possible Role for Stress-Activated Protein Kinase Signaling Pathway and Fas Expression

  Tian-Li Yue, Xinkang Wang, Calvert S. Louden, Shalley Gupta, Kodandaram Pillarisetti, Juan-Li Gu, Timothy K. Hart, Paul G. Lysko and Giora Z. Feuerstein

  Molecular Pharmacology June 1997, 51 (6) 951-962; DOI: https://doi.org/10.1124/mol.51.6.951
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  DNA Elements Recognizing NF-Y and Sp1 Regulate the Human Multidrug-Resistance Gene Promoter

  Rebecca Sundseth, Gene Macdonald, Jenny Ting and A. Christie King

  Molecular Pharmacology June 1997, 51 (6) 963-971; DOI: https://doi.org/10.1124/mol.51.6.963
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  Induction of Apoptosis by Retinoids and Retinoic Acid Receptor γ-Selective Compounds in Mouse Thymocytes through a Novel Apoptosis Pathway

  Zsuzsa Szondy, Uwe Reichert, Jean-Michel Bernardon, Serge Michel, Réka Tóth, Philippe Ancian, Eva Ajzner and Laszlo Fesus

  Molecular Pharmacology June 1997, 51 (6) 972-982; DOI: https://doi.org/10.1124/mol.51.6.972
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  Histamine Modulates the Expression of c-fosthrough Cyclic AMP Production via the H₂ Receptor in the Human Promonocytic Cell Line U937

  Carina Shayo, Carlos Davio, Andres Brodsky, Alejandro G. Mladovan, Bibiana Lemos Legnazzi, Elena Rivera and Alberto Baldi

  Molecular Pharmacology June 1997, 51 (6) 983-990; DOI: https://doi.org/10.1124/mol.51.6.983
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  A Dominant Negative Mutant of the G Protein-Coupled Receptor Kinase 2 Selectively Attenuates Adenosine A₂ Receptor Desensitization

  Stuart J. Mundell, Jeffrey L. Benovic and Eamonn Kelly

  Molecular Pharmacology June 1997, 51 (6) 991-998; DOI: https://doi.org/10.1124/mol.51.6.991
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  Role of Conserved Histidines in Catalytic Activity and Inhibitor Binding of Human Recombinant Phosphodiesterase 4A

  Susanne Jacobitz, M. Dominic Ryan, Megan M. McLaughlin, George P. Livi, Walter E. Dewolf and Theodore J. Torphy

  Molecular Pharmacology June 1997, 51 (6) 999-1006; DOI: https://doi.org/10.1124/mol.51.6.999
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  Stimulatory Roles of Muscarinic Acetylcholine Receptors on T Cell Antigen Receptor/CD3 Complex-Mediated Interleukin-2 Production in Human Peripheral Blood Lymphocytes

  Hiromichi Fujino, Yoshihisa Kitamura, Takeshi Yada, Takashi Uehara and Yasuyuki Nomura

  Molecular Pharmacology June 1997, 51 (6) 1007-1014; DOI: https://doi.org/10.1124/mol.51.6.1007
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  Differential Sensitivity of RecombinantN-Methyl-d-Aspartate Receptor Subtypes to Zinc Inhibition

  Nansheng Chen, Ali Moshaver and Lynn A. Raymond

  Molecular Pharmacology June 1997, 51 (6) 1015-1023; DOI: https://doi.org/10.1124/mol.51.6.1015
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  P-Glycoprotein Substrates and Antagonists Cluster into Two Distinct Groups

  Stefania Scala, Nadia Akhmed, U. S. Rao, Ken Paull, Lu-Bin Lan, Bruce Dickstein, Jong-Seok Lee, Galal H. Elgemeie, Wilfred D. Stein and Susan E. Bates

  Molecular Pharmacology June 1997, 51 (6) 1024-1033; DOI: https://doi.org/10.1124/mol.51.6.1024
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  ATP-Dependent Transport of Aflatoxin B₁ and Its Glutathione Conjugates by the Product of the Multidrug Resistance Protein (MRP) Gene

  Douglas W. Loe, Richard K. Stewart, Thomas E. Massey, Roger G. Deeley and Susan P. C. Cole

  Molecular Pharmacology June 1997, 51 (6) 1034-1041; DOI: https://doi.org/10.1124/mol.51.6.1034
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  Purification of a New Dimeric Protein from Cliona vastifica Sponge, which Specifically Blocks a Non-L-Type Calcium Channel in Mouse Duodenal Myocytes

  Jean-Luc Morel, Hervé Drobecq, Pierre Sautiere, André Tartar, Jean Mironneau, Janti Qar, Jean-Louis Lavie and Michel Hugues

  Molecular Pharmacology June 1997, 51 (6) 1042-1052; DOI: https://doi.org/10.1124/mol.51.6.1042
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  Relationship between Lethal Effects and Topoisomerase II-Mediated Double-Stranded DNA Breaks Produced by Anthracyclines with Different Sequence Specificity

  Monica Binaschi, Giovanni Capranico, Laura Dal Bo and Franco Zunino

  Molecular Pharmacology June 1997, 51 (6) 1053-1059; DOI: https://doi.org/10.1124/mol.51.6.1053
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  Somatostatin₅ Receptor-Mediated [³⁵S]Guanosine-5′-O-(3-thio)triphosphate Binding: Agonist Potencies and the Influence of Sodium Chloride on Intrinsic Activity

  Andrea J. Williams, Anton D. Michel, Wasyl Feniuk and Patrick P. A. Humphrey

  Molecular Pharmacology June 1997, 51 (6) 1060-1069; DOI: https://doi.org/10.1124/mol.51.6.1060
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  Substrate Dependence of Angiotensin I-Converting Enzyme Inhibition: Captopril Displays a Partial Selectivity for Inhibition ofN-Acetyl-Seryl-Aspartyl-Lysyl-Proline Hydrolysis Compared with That of Angiotensin I^·

  Annie Michaud, Tracy A. Williams, Marie-Thérèse Chauvet and Pierre Corvol

  Molecular Pharmacology June 1997, 51 (6) 1070-1076; DOI: https://doi.org/10.1124/mol.51.6.1070
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  Carbamazepine Inhibition of Neuronal Na⁺ Currents: Quantitative Distinction from Phenytoin and Possible Therapeutic Implications

  Chung-Chin Kuo, Ren-Shiang Chen, Lu Lu and Rong-Chi Chen

  Molecular Pharmacology June 1997, 51 (6) 1077-1083; DOI: https://doi.org/10.1124/mol.51.6.1077